Oval Cell Marker Antibody (OC2-4E8) [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ICC/IF, IHC, IHC-Fr
Clone
OC2-4E8
Clonality
Monoclonal
Host
Rat

Oval Cell Marker Antibody (OC2-4E8) [Biotin] Summary

Description
This product is provided as conjugated tissue culture supernatant. Due to the crude preparation of the antibody material, excess dye may remain in the final product. We highly recommend taking necessary precautions, such as adding additional wash steps and running proper controls.
Immunogen
Nonparenchymal cells from DDC-treated mice to induce the oval cell response.
Localization
Cell surface
Marker
Hepatic periductal cell Marker
Specificity
Specific for both proliferating and normal hepatic periductal cells.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
Biotin
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Tissue culture supernatant

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
This Oval Cell Marker (OC2-4E8) antibody is useful for Immunohistochemistry on acetone fixed frozen sections and Flow cytometry. Immunocytochemistry/Immunofluorescence was reported in scientific literature.
Readout System

Reactivity Notes

Mouse.

Alternate Names for Oval Cell Marker Antibody (OC2-4E8) [Biotin]

  • macrophage inhibitory cytokine-1

Background

Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Oval Cell Marker Antibody (NBP1-18971B) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NBP1-18971APC
DyLight 350 Labeled NBP1-18971UV
DyLight 405 Labeled NBP1-18971V
DyLight 488 Labeled NBP1-18971G
DyLight 550 Labeled NBP1-18971R
DyLight 650 Labeled NBP1-18971C
DyLight 680 Labeled NBP1-18971FR
DyLight 755 Labeled NBP1-18971IR
FITC Labeled NBP1-18971F
HRP Labeled NBP1-18971H
PE Labeled NBP1-18971PE
PerCP Labeled NBP1-18971PCP

Additional Oval Cell Marker Products

Oval Cell Marker NBP1-18971B

Research Areas for Oval Cell Marker Antibody (NBP1-18971B)

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