HIV-1 gp120 Antibody [Biotin] Summary
Purified gp120 from strain IIIB
NB100-66437 is specific for gp120, an exterior envelope glycoprotein on the surface of the virus particle that acts as a receptor for CD4 and chemokine receptors on macrophages and T-lymphocytes. It does not react with human T cells, B cells, normal bovine serum or normal human serum. In western blotting a predominant gp120 band is observed.
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
Alternate Names for HIV-1 gp120 Antibody [Biotin]
- Envelope surface glycoprotein gp120
- gp120 glycoprotein
- Human immunodeficiency virus 1
- Surface protein
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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