Species: V-Vi
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: V-Vi
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: V-Vi
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: V-Vi
Applications: ELISA
Host: Rabbit Monoclonal
Description
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Bioinformatics
| Uniprot |
Virus
|
| Product By Gene ID |
155971 |
| Alternate Names |
- Envelope surface glycoprotein gp120
- gp120 glycoprotein
- gp120
- Human immunodeficiency virus 1
- SU
- Surface protein
|
Research Areas for HIV-1 gp120
Find related products by research area and learn more about each of the different research areas below.
Virology, Bacteria and Parasites
![Sandwich ELISA HIV-1 gp120 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/HIV-1-gp120-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79627-img0001.jpg)