Hepatitis C Virus Core Antigen Antibody (C7-50) [Janelia Fluor® 549]

• Reactivity: Hu, Mu, V-Vi
• Applications: WB, ELISA, Flow, IHC, IP, ICC/IF
• Clone: C7-50
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

Hepatitis C Virus Core Antigen Antibody (C7-50) [Janelia Fluor® 549] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Purified HCV core-GST fusion protein (genotype 1b).
• Epitope: This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.
• Specificity: Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: POLY
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB120-2740. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Human reactivity reported in literature (PMID: 16940534). Mouse reactivity reported in literature (PMID: 22984515).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Hepatitis C Virus Core Antigen Antibody (C7-50) [Janelia Fluor® 549]

• Core protein p19
• HCcAg
• HCV core antigen
• HCV core protein

Background

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: POLY