Hepatitis C Virus Core Antigen Antibody (C7-50) - BSA Free

• Reactivity: Hu, Mu, V-Vi
• Applications: WB, ELISA, Flow, IHC, IP, ICC/IF
• Clone: C7-50
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Hepatitis C Virus Core Antigen Antibody (C7-50) - BSA Free Summary

• Immunogen: Purified HCV core-GST fusion protein (genotype 1b).
• Epitope: This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.
• Specificity: Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: POLY
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Flow Cytometry 1:100
  • Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1 ug/mL
• Application Notes: IP usage was reported in scientific literature (PMID: 16940534). IHC usage reported in scientific literature (PMID: 15159022). WB: Detects a single ~21 kDa protein representing HCV core protein in various transfected cell lines. IF: Staining of HCV core protein in transfected chimp hepatocytes yields a staining pattern consistent with cytoplasmic and vesicular staining.

Reactivity Notes

Human reactivity reported in literature (PMID: 16940534). Mouse reactivity reported in literature (PMID: 22984515).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Hepatitis C Virus Core Antigen Antibody (C7-50) - BSA Free

• Core protein p19
• HCcAg
• HCV core antigen
• HCV core protein

Background

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Hepatitis C Virus Core Antigen Antibody (NB120-2740)(1)

Publication using NB120-2740

• Zhao L, Sun X, Chen L et al. Hepatitis C Virus Core Protein Promotes the Metastasis of Human Hepatocytes by Activating the MAPK/ERK/PEA3-SRF/c-Fos/MMPs Axis Archives of medical research 2022-07-01 [PMID: 35817647] (WB, Human)

Review for Hepatitis C Virus Core Antigen Antibody (NB120-2740) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer ELISA Human 10/03/2018

Summary

• Application: ELISA
• Sample Tested: Human antibody
• Species: Human
• Lot: TB261345

Bioinformatics

• Gene Symbol: POLY