Hepatitis C Virus Core Antigen Antibody (C7-50) [Allophycocyanin/Cy7]

• Reactivity: Hu, Mu, V-Vi
• Applications: Flow
• Clone: C7-50
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin/Cy7

Hepatitis C Virus Core Antigen Antibody (C7-50) [Allophycocyanin/Cy7] Summary

• Immunogen: Purified HCV core-GST fusion protein (genotype 1b).
• Epitope: This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.
• Specificity: Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: POLY
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Reactivity Notes

Human reactivity reported in literature (PMID: 16940534). Mouse reactivity reported in literature (PMID: 22984515).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Hepatitis C Virus Core Antigen Antibody (C7-50) [Allophycocyanin/Cy7]

• Core protein p19
• HCcAg
• HCV core antigen
• HCV core protein

Background

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: POLY