Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC-Fr, IHC-P
Clone
SE-1
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [Biotin] Summary

Immunogen
Rat Hepatic Sinusoidal Endothelial Cells
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
This Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) is useful for Immunohistochemistry and Western blot, where a band can be seen around 45-50 kDa. For IHC use neutral buffered formalin fixated (perfusion fixation is recommended) paraffin embedded tissues after proteinase K treatment or acetone fixed frozen sections.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [Biotin]

  • Hepatic cells
  • Hepatic Sinusoidal Endothelial Cells
  • HSE
  • SE1
  • Sinusoidal Endothelial Cells

Background

Among the vascular endothelial cells, hepatic sinusoidal endothelial (HSE) cells are morphologically unique because they have open fenestrations in their cytoplasm and lack basal lamina. This unique structure is assumed to facilitate the exchange and transport of various substances between blood and hepatocytes through the space of Disse. It has been suggested that the formation of this structure is regulated by hepatocyte-related soluble factors or by the extracellular matrix. This antibody has observed no cross-reactivity with other types of endothelial cells or non-endothelial cells. By immunoelectron microscopy, the antigen recognized by this antibody was localized to the membrane surface of HSE. This antibody may be a useful marker to study the role of HSE in various pathophysiological conditions of the liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Hepatic Sinusoidal Endothelial Cells Antibody (NB110-68095B) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB110-68095APC
DyLight 350 Labeled NB110-68095UV
DyLight 405 Labeled NB110-68095V
DyLight 488 Labeled NB110-68095G
DyLight 550 Labeled NB110-68095R
DyLight 650 Labeled NB110-68095C
DyLight 680 Labeled NB110-68095FR
DyLight 755 Labeled NB110-68095IR
FITC Labeled NB110-68095F
HRP Labeled NB110-68095H
PE Labeled NB110-68095PE

Additional Hepatic Sinusoidal Endothelial Cells Products

Hepatic Sinusoidal Endothelial Cells NB110-68095B

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