Helicobacter Pylori Antibody


Immunohistochemistry-Paraffin: Helicobacter Pylori Antibody [NBP2-29479] - Formalin-fixed, paraffin-embedded human stomach stained with Helicobacter pylori antibody (1:200), peroxidase-conjugate and DAB chromogen. ...read more

Product Details

Reactivity Hu, Mu, Bv, ChSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-P
Please see the vial label for concentration. If unlisted please contact technical services.

Helicobacter Pylori Antibody Summary

Total Helicobacter pylori lysate was used as immunogen for this antibody.
The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcinoma and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
PBS with 0.05% BSA.
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified


Application Notes
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Alternate Names for Helicobacter Pylori Antibody

  • H. pylori


Helicobacter pylori (H.pylori) is a gram-negative, microaerophil bacterium found in the stomach. Although Helicobacter pylori is present in the upper gastrointestinal track of more than 50% of the world's population, about 80% of people infected with Helicobacter pylori are asymptomatic. However, Helicobacter pylori is also strongly linked to disease and is thought to have evolved to penetrate the mucoid lining of the stomach. Penetrating the mucosal layer can cause considerable damage to mucosa, and chronic infection can result in or contribute to chronic gastritis, gastric ulcers as well as duodenal ulcers.

There is also strong evidence that Helicobacter pylori plays a causal role in the development of some stomach cancers, likely through chronic infection. However, Helicobacter pylori is also thought to play a role in normal stomach homeostasis which could help explain the large percent of people who have some level of Helicobacter pylori in their gut. The antibody can be used as an ancillary tool for identifying Helicobacter pylori by immunohistochemistry of tissue sections and may help determine if disease is linked to active infection. The antibody can also be used to study the presence of Helicobacter pylori in healthy tissue and may be a useful biomarker for further understanding the role of microbes in stomach homeostasis.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Additional Helicobacter Pylori Antibody Products

Helicobacter Pylori NBP2-29479

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