GPR4 Antibody

Immunohistochemistry-Paraffin: GPR4 Antibody [NBP1-87463] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Product Discontinued

GPR4 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: DELFRDRYNHTFCFEKFPMEGWVAWMN
• Predicted Species: Mouse (96%), Rat (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPR4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for GPR4 Antibody

• G protein-coupled receptor 4
• GPR19
• GPR4
• G-protein coupled receptor 19
• G-protein coupled receptor 4

Background

GPR4 is a Lysophospholipid/Lysosphingolipid receptor. Recently, GPR4 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003). GPR4 has been reported in kidney, heart, and especially lung, where it is at least five-fold greater than in other tissues (Mahadevan et al., 1995). ESTs have been isolated from brain, colon, kidney, lung, and melanocyte/uterus/fetal heart libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPR4