EFCAB4A Antibody - BSA Free

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Western Blot: EFCAB4A Antibody [NBP1-76492] - human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

EFCAB4A Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit EFCAB4A Antibody - BSA Free (NBP1-76492) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A. The immunogen is located within amino acids 290 - 340 of EFCAB4A. Amino Acid Squence: ESEARGRQEQTQRDV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRACR2B
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Western Blot 1-2 ug/ml
Control Peptide
EFCAB4A Peptide (NBP1-76492PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for EFCAB4A Antibody - BSA Free

  • Calcium release-activated calcium channel regulator 2B
  • CRAC channel regulator 2B
  • CRACR2B
  • EF-hand calcium binding domain 4A
  • EF-hand calcium-binding domain-containing protein 4A
  • FLJ46033
  • MGC45840
  • MGC88858

Background

EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CRACR2B
Uniprot