Adenylate Cyclase 6 Antibody

Images

 
Western Blot: E coli-derived fusion protein as test antigen. Affi-anti-ATP7A IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-ADCY6)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Chicken
Conjugate
Unconjugated

Order Details

Adenylate Cyclase 6 Antibody Summary

Immunogen
The immunogen for this antibody was a sequence from 1a.a. to 121a.a. from Adenylate cyclase type 6(a 1168a.a. long protein)
Localization
Membrane; multi-pass membrane protein.
Specificity
Adenylate Cyclase 6
Clonality
Polyclonal
Host
Chicken
Gene
ADCY6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affi-anti-ATP7A IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Reactivity Notes

This antibody is reactive against Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for Adenylate Cyclase 6 Antibody

  • AC6
  • adenylate cyclase 6
  • adenylate cyclase type 6
  • Adenylate cyclase type VI
  • Adenylyl cyclase 6
  • ATP pyrophosphate-lyase 6
  • Ca(2+)-inhibitable adenylyl cyclase
  • DKFZp779F075
  • EC 4.6.1.1
  • KIAA0422

Background

The membrane-bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein-coupled receptors. Eight human AC isoforms (AC1 through AC4), encoded by separate genes, have been identified up to now. Most of the adenylate cyclase genes are comprise of 11-26 exons and distributed over a q6-430 kb. Majority of the adenylate cyclases previously described are expressed discretely in defined peripheral tissues, the type 4 adenylate cyclase (AC4) is apparently expressed in a variety of peripheral tissues and in the central nervous system, mainly in olfactory system. AC5 is localized on photoreceptor cells and are also designated as GC1 and GC2. The AC5 protein resembles the other adenylyl cyclases in its predicted and proposed structure. AC5 resembles the type 6 (AC6) adenylyl cyclase in its amino acid sequence but becomes divergent at N and C-terminal ends. The AC5 and AC6 proteins are co-localized in most of the visual organs (photoreceptor cells) are associated with other protein complexes. Both AC5 and AC6 enzymes play an important role in synaptic plasticity by coordinating overlapping synaptic inputs from Gs and Gi coupled receptor stimulation. Membrane-bound. calcium-inhibitable adenylyl cyclase (By similarity).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADCY6
Entrez
Uniprot