Sort By:

Products (2)

page of 1

Caspase-11/Caspase-4 Antibodies

We offer Caspase-11/Caspase-4 Antibodies for use in common research applications: Immunocytochemistry, Western Blot. Each Caspase-11/Caspase-4 Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our Caspase-11/Caspase-4 Antibodies can be used in a variety of model species: Mouse. Use the list below to choose the Caspase-11/Caspase-4 Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Choose from our Caspase-11/Caspase-4 monoclonal antibodies.

Alternate Names for Caspase-11/Caspase-4 Antibodies

anti-Caspase-11/Caspase-4 antibody, anti-Casp4 antibody

2 Results for "caspase-11-caspase-4" in Primary Antibodies

MAB8648

Caspase-11/Caspase-4 Antibody (1172C) [Unconjugated]

(1 Publication)

100 μg

MAB8648

Western blot shows lysates of mouse splenocytes untreated (-) or treated (+) with LPS. PVDF membrane was probed with 1 µg/mL of Rabbit Anti-Mouse Caspase-11/Caspase-4 Monoclonal Antibody (Catalog # MAB8648) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # HAF008). Specific bands were detected for Caspase-11/Caspase-4 at approximately 36, 44, and 46 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

<b>Biological Strategies Validation. </b>Pro-casp-1, casp-11, NLRP3, gasdermin D (GSDMD) expression were assessed by western blot. Statistical significance was determined by using Student’s t-test or one-way ANOVA. Asterisks indicate p-values *=p 0.05. Image collected and cropped by CiteAb from the following open publication (//dx.plos.org/10.1371/journal.ppat.1012167), licensed under a CC-BY license. Not internally tested by R&D Systems.

NAD+ specifically inhibits the non-canonical inflammasome by targeting caspase-11.Bone marrow was isolated from mice and bone marrow-derived macrophages (BMDMs) were differentiated in vitro. Subsequently, BMDMs were cultured in the presence of NAD+ or PBS. BMDMs were then primed with either Pam3CSK4 or lipopolysaccharide (LPS) O111:B4. Next primed BMDMs were stimulated with ATP or LPS and cholera toxin B (CTB). (A) Pro-casp-1, pro-casp-11, casp-11, NLRP3, casp-1, IL1 beta , and gasdermin D (GSDMD) expression were determined using western blot and (B) IL-1 beta secretion and LDH release were assessed in the supernatant. Column plots display mean with standard deviation (n=5-8). Image collected and cropped by CiteAb from the following open publication (//elifesciences.org/articles/88686), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reactivity:

Mu

Species Glossary

Reactivity: Mu

Applications:

Applications:

Host:

Rabbit Monoclonal

Host: Rabbit Monoclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Validated by:

Validated by:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB8648U-100UG
Alexa Fluor 405	FAB8648V-100UG
Alexa Fluor 488	FAB8648G-100UG
Alexa Fluor 532	FAB8648X-100UG
Alexa Fluor 594	FAB8648T-100UG
Alexa Fluor 647	FAB8648R-100UG
Alexa Fluor 700	FAB8648N-100UG
Alexa Fluor 750	FAB8648S-100UG
Allophycocyanin	FAB8648A
Biotin	FAB8648B
CoraFluor 1	FAB8648CL1
DyLight 350	FAB8648D
DyLight 405	FAB8648E
DyLight 488	FAB8648K
DyLight 550	FAB8648L
DyLight 594	FAB8648M
DyLight 650	FAB8648W
DyLight 680	FAB8648Y
DyLight 755	FAB8648Z
FITC	FAB8648F
HRP	FAB8648H
Janelia Fluor 525	FAB8648JF525
Janelia Fluor 549	FAB8648I
Janelia Fluor 646	FAB8648J
Janelia Fluor 669	FAB8648JF669
PE	FAB8648P
PerCP	FAB8648C
mFluor Violet 450 SE	FAB8648MFV450
mFluor Violet 500 SE	FAB8648MFV500
mFluor Violet 610 SE	FAB8648MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	MAB8648-SP

compare

(select up to 3 products from this page to compare)

MAB86481

Caspase-11/Caspase-4 Antibody (919916) [Unconjugated]

(1 Publication)

100 μg

MAB86481

Caspase-11/Caspase-4 was detected in immersion fixed mouse splenocytes treated with LPS using Rat Anti-Mouse Caspase-11/Caspase-4 Monoclonal Antibody (Catalog # MAB86481) at 25 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Reactivity:

Mu

Species Glossary

Reactivity: Mu

Applications:

Applications:

Host:

Rat Monoclonal

Host: Rat Monoclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB86481U-100UG
Alexa Fluor 405	FAB86481V-100UG
Alexa Fluor 488	FAB86481G-100UG
Alexa Fluor 532	FAB86481X-100UG
Alexa Fluor 594	FAB86481T-100UG
Alexa Fluor 647	FAB86481R-100UG
Alexa Fluor 700	FAB86481N-100UG
Alexa Fluor 750	FAB86481S-100UG
Allophycocyanin	FAB86481A
Biotin	FAB86481B
CoraFluor 1	FAB86481CL1
DyLight 350	FAB86481D
DyLight 405	FAB86481E
DyLight 488	FAB86481K
DyLight 550	FAB86481L
DyLight 594	FAB86481M
DyLight 650	FAB86481W
DyLight 680	FAB86481Y
DyLight 755	FAB86481Z
FITC	FAB86481F
HRP	FAB86481H
Janelia Fluor 525	FAB86481JF525
Janelia Fluor 549	FAB86481I
Janelia Fluor 646	FAB86481J
Janelia Fluor 669	FAB86481JF669
PE	FAB86481P
PerCP	FAB86481C
mFluor Violet 450 SE	FAB86481MFV450
mFluor Violet 500 SE	FAB86481MFV500
mFluor Violet 610 SE	FAB86481MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	MAB86481-SP

compare

(select up to 3 products from this page to compare)

page of 1

Popular Products	Company Information	Support	Stay Connected
Antibodies Secondary Antibodies Isotype Controls Proteins and Peptides ELISA Kits Sample Size New Products	About Us Careers Novus Guarantee Contact Us Our Team	Technical Support FAQs Protocols

Visit our other sites

©2026 Novus Biologicals, All Rights Reserved.