PGC-1 beta Products

Description

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. PGC-1 beta is also involved in activation of nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. Ectopic expression of this protein has been shown to lead to increased mitochondrial numbers and basal oxygen consumption.

Bioinformatics

Uniprot	NM_133263 Human NP_573570 Human Q86YN6 Human
Product By Gene ID	133522
Alternate Names	DKFZp686C1790 ERRL1 PERCFLJ14284 peroxisome proliferator-activated receptor gamma, coactivator 1 beta PGC1 PGC1Bgamma, coactivator 1, beta PPARGC1

Research Areas for PGC-1 beta

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Chromatin Research
Diabetes Research
Hypoxia
Lipid and Metabolism
Mitochondrial Markers
Neuroscience
Signal Transduction