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Park7/DJ-1 Products

Antibodies
Park7/DJ-1 Antibody
Park7/DJ-1 Antibody
NB100-1194
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Goat Polyclonal
Park7/DJ-1 Antibody [Unconjug ...
Park7/DJ-1 Antibody [Unconjugated]
AF3995
HAF109). A specific band was detected for Park7/DJ-1 at approximately 22 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot Park7/DJ-1 Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry Park7/DJ-1 Antibody [Unconjugated]
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank"> Simple Western Park7/DJ-1 Antibody [Unconjugated]
HAF017). A specific band was detected for Park7/DJ-1 at approximately 23 kDa (as indicated) in the parental HEK293T cell line, but is not detectable in knockout HEK293T cell line. GAPDH (AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated Park7/DJ-1 Antibody [Unconjugated]
VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in neurons. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry Park7/DJ-1 Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, IHC, ICC/IF, KO
Host: Goat Polyclonal
ELISA Kits
Human Park7/DJ-1 DuoSet ELISA ...
Human Park7/DJ-1 DuoSet ELISA, 15 ...
DY3995
Species: Hu
Applications: ELISA
Mouse Park7/DJ-1 DuoSet ELISA ...
Mouse Park7/DJ-1 DuoSet ELISA, 5 P...
DY8136-05
Species: Mu
Applications: ELISA
Lysates
Park7/DJ-1 Overexpression Lys ...
Park7/DJ-1 Overexpression Lysate
NBL1-14106
Species: Hu
Applications: WB
Proteins
Park7/DJ-1 Antibody Blocking ...
Park7/DJ-1 Antibody Blocking Peptide
NB300-270PEP
Applications: AC
Recombinant Human Park7/DJ-1 ...
Recombinant Human Park7/DJ-1 His P...
NBC1-18334
Species: Hu
Applications: PAGE
Recombinant Mouse Park7/DJ-1 ...
Recombinant Mouse Park7/DJ-1 His P...
NBP2-59523
Species: Mu
Applications: PAGE

Description

PARK7, also known as DJ-1, is a member of the peptidase C56 protein family. The PARK-7 protein is a positive regulator of androgen receptor-dependent transcription. It has also been reported to be a potential sensor for oxidative stress, a redox-sensitive chaperone, and a key protein for preventing neuronal oxidative stress and cell death.

PARK7 is highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, and is detected at slightly lower levels in placenta and brain. The protein is also detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa.

Defects in this gene cause the autosomal recessive neurodegenerative disorder early-onset Parkinson's disease 7.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 11315
Alternate Names
  • DJ-1
  • DJ1FLJ34360
  • EC 3.4
  • FLJ27376
  • FLJ92274
  • Oncogene DJ1
  • Parkinson disease (autosomal recessive, early onset) 7
  • Parkinson disease protein 7
  • protein DJ-1

Research Areas for Park7/DJ-1

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Apoptosis
Cancer
DNA replication, Transcription, Translation and Splicing
Neurodegeneration
Neuronal Cell Markers
Neuroscience
Signal Transduction
Tumor Suppressors

Related Park7/DJ-1 Blog Posts

Check out the latest blog posts on Park7/DJ-1.
Park7/DJ-1: A Reliable Biomarker for Parkinson's Disease?
The product of the Parkinson's disease 7 (Park7/DJ-1) gene belongs to the peptidase C56 family of proteins and appears to have two transcriptional variants. It is a positive regulator of androgen receptor-dependent transcription, and some evidence sug...    Read more.
Read more Park7/DJ-1 related blogs.