Park7/DJ-1 Products

Description

PARK7, also known as DJ-1, is a member of the peptidase C56 protein family. The PARK-7 protein is a positive regulator of androgen receptor-dependent transcription. It has also been reported to be a potential sensor for oxidative stress, a redox-sensitive chaperone, and a key protein for preventing neuronal oxidative stress and cell death.

PARK7 is highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, and is detected at slightly lower levels in placenta and brain. The protein is also detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa.

Defects in this gene cause the autosomal recessive neurodegenerative disorder early-onset Parkinson's disease 7.

Bioinformatics

Uniprot	AAH08188 Human NM_007262 Human NP_009193 Human NP_009193 Human NP_009193.2 Human Q99497 Human Q99497 Human
Product By Gene ID	11315
Alternate Names	DJ-1 DJ1FLJ34360 EC 3.4 FLJ27376 FLJ92274 Oncogene DJ1 Parkinson disease (autosomal recessive, early onset) 7 Parkinson disease protein 7 protein DJ-1

Research Areas for Park7/DJ-1

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Apoptosis
Cancer
DNA replication, Transcription, Translation and Splicing
Neurodegeneration
Neuronal Cell Markers
Neuroscience
Signal Transduction
Tumor Suppressors

Related Park7/DJ-1 Blog Posts

Check out the latest blog posts on Park7/DJ-1.

Park7/DJ-1: A Reliable Biomarker for Parkinson's Disease? The product of the Parkinson's disease 7 (Park7/DJ-1) gene belongs to the peptidase C56 family of proteins and appears to have two transcriptional variants. It is a positive regulator of androgen receptor-dependent transcription, and some evidence sug...    Read more.

Read more Park7/DJ-1 related blogs.