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![Western Blot: TXNL6 Overexpression Lysate (Adult Normal) [NBP2-05652] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TXNL6.](http://images.novusbio.com/fullsize/TXNL6-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-05652-img0001.jpg "Western Blot: TXNL6 Overexpression Lysate (Adult Normal) [NBP2-05652] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TXNL6.")
![Flow Cytometry: Polarity Sensitive Indicator of Viability Apoptosis Kit [IANBD] [NBP2-29611] - pSIVA-IANBD(TM) + PI shows progressive population staining as cells move from healthy towards death.](http://images.novusbio.com/fullsize/Polarity-Sensitive-Indicator-of-Viability-Apoptosis-Kit-[IANBD]-Flow-Cytometry-NBP2-29611-img0002.jpg "Flow Cytometry: Polarity Sensitive Indicator of Viability Apoptosis Kit [IANBD] [NBP2-29611] - pSIVA-IANBD(TM) + PI shows progressive population staining as cells move from healthy towards death.")
![Flow Cytometry: Polarity Sensitive Indicator of Viability Apoptosis Kit [IANBD] [NBP2-29611] - pSIVA-IANBD(TM) shows progressive population staining as cells move from healthy towards death.](http://images.novusbio.com/fullsize/Polarity-Sensitive-Indicator-of-Viability-Apoptosis-Kit-[IANBD]-Flow-Cytometry-NBP2-29611-img0001.jpg)
![In vivo assay: IKK gamma Inhibitor Peptide Set [NBP2-26504] - NBD peptide blocks constitutive NF-kB as shown by EMSA. U266 cells were treated with 100 uM of control or NBD peptide for different time periods. Nuclear extracts were isolated and checked for NF-kB-DNA binding activity.](http://images.novusbio.com/fullsize/IKK-gamma-Inhibitor-Peptide-Set-In-vivo-assay-NBP2-26504-img0010.jpg "In vivo assay: IKK gamma Inhibitor Peptide Set [NBP2-26504] - NBD peptide blocks constitutive NF-kB as shown by EMSA. U266 cells were treated with 100 uM of control or NBD peptide for different time periods. Nuclear extracts were isolated and checked for NF-kB-DNA binding activity.")
![In vivo assay: IKK gamma Inhibitor Peptide Set [NBP2-26504] - NBD peptide blocks constitutive NF-kB activation in human multiple myeloma cells. U266 cells were treated with 100 uM of control (A & B) or NBD peptide (C & D) for 12 hr, cytospun, plated on glass slides, air dried for 1 hr at room temperature and fixed with cold acetone. Slides were blocked with 5% normal goat serum for 1 hr and then incubated with rabbit polyclonal anti-human p65 antibody (A & C) followed by Ig-Alexa 594 second step. In control peptide treated cells, p65 translocates to nucleus (A), whereas NBD peptide prevents translocation of p65 into the nucleus (C). B & D: Nuclear staining with DNA binding dye.](http://images.novusbio.com/fullsize/IKK-gamma-Inhibitor-Peptide-Set-In-vivo-assay-NBP2-26504-img0012.jpg)
![IKK gamma Inhibitor Peptide Set [NBP2-26504] - The IKK complex consists of IKKalpha + IKKbeta+ NEMO. NEMO (IKKgamma/NF-kB Essential MOdulator) is a scaffold protein required for the kinase activity of IKKalpha + IKKbeta. NBD (NEMO Binding Domain) inhibits formation of the IKK complex (IKKalpha + IKKbeta+ NEMO) by binding to NEMO and blocking IKK complex formation. In this regard, NBD is considered to be an 'IKKalpha and IKKBeta decoy' Blocking IKK complex formation suppresses downstream events in the NF-kB signaling pathway that rely on the IKK complex including phosphorylation of IkBalpha, and subsequence IkBalpha ubiquination, degradation and release of NF-kB. Hence, NF-kB is retained in the cytoplasm in its inactive state.](http://images.novusbio.com/fullsize/IKK-gamma-Inhibitor-Peptide-Set-NBP2-26504-img0014.jpg)
![Functional (Inhibition): IKK gamma Inhibitor Peptide Set [NBP2-26504] - TLR5/NF-kB/SEAPorter HEK 293 (NBP2-26277) cells were plated in 96-well plates at 5 x 10^4 cells/well for 16 h. Cells were preincubated with different concentrations (0, 1, 5, 10, 25 and 50 uM) of Inhibitory Peptide (NBP2-26504) and Control Peptide (NBP2-29334) for 1 h. Cells were then stimulated with 1 ng/ml Flagellin (NBP2-25289) for 24 h. Secreted alkaline phosphatase (SEAP) was analyzed using SEAPorter Assay Kit (NBP2-25285). *p < 0.05 versus control peptide at the corresponding concentrations (Mann-Whitney U test).](http://images.novusbio.com/fullsize/IKK-gamma-Inhibitor-Peptide-Set-Functional-Inhibition-NBP2-26504-img0016.jpg)
![Flow Cytometry: Propidium Iodide [NBP2-31155] - Image from verified customer review.](http://images.novusbio.com/fullsize/Propidium-Iodide-Flow-Cytometry-NBP2-31155-img0003.jpg "Flow Cytometry: Propidium Iodide [NBP2-31155] - Image from verified customer review.")
![Propidium iodide Solution [NBP2-31155] - Propidium iodide Solution](http://images.novusbio.com/fullsize/Propidium-iodide-Solution-NBP2-31155-img0002.jpg)
![Cellular Imaging: Propidium Iodide [NBP2-31155] - MDA-MB468 cells stained with Live green dye (Calcein) and dead PI dyes (red) after 5 days of drug treatment. Image from verified customer review.](http://images.novusbio.com/fullsize/Propidium-Iodide-Cellular-Imaging-NBP2-31155-img0004.jpg)
![Flow Cytometry: 7-Aminoactinomycin D Solution [NBP2-29446] - Mouse lymphocytes were unstained (left) or stained (right) with 7-AAD. Without 7-AAD, dead cells cannot be visualized. With 7-AAD, dead cells can be visualized and excluded from further analysis.](http://images.novusbio.com/fullsize/7-Aminoactinomycin-D-Solution-Flow-Cytometry-NBP2-29446-img0005.jpg "Flow Cytometry: 7-Aminoactinomycin D Solution [NBP2-29446] - Mouse lymphocytes were unstained (left) or stained (right) with 7-AAD. Without 7-AAD, dead cells cannot be visualized. With 7-AAD, dead cells can be visualized and excluded from further analysis.")
![7-Aminoactinomycin D Solution [NBP2-29446] - 7-Aminoactinomycin D [NBP2-29446]](http://images.novusbio.com/fullsize/7-Aminoactinomycin-D-Solution-NBP2-29446-img0003.jpg)