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SORCS3 Products By Gene Name

8 Results for "SORCS3"
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MAB3067

SorCS3 Antibody (339624)

(4 Publications)
100 μg
MAB3067
Altered subcellular localization of TrkB in primary neurons and brains from S1/3 KO miceAWorkflow of the cell surface proteome analysis in primary neurons.BResults of quantitative label‐free proteomics comparing the surface proteomes of WT and S1/3 KO primary cortical neurons. Plot represents –log10(P‐value) and log2 (relative levels S1/3KO/WT) obtained for each protein. For proteins that were detected in either S1/3 KO or WT samples only, the log2(S1/3 KO/WT) was set to 10 or ‐10, respectively. Threshold values are 1.3 for –log10(P‐value) and ±0.3 for log2(S1/3 KO/WT). Proteins showing higher (green) or lower (red) surface levels in S1/3 KO as compared to WT neurons are indicated. Proteins with unchanged cell surface levels are indicated in blue. n = 3 biological replicates/group (with each biological replicate run in two technical replicates).CScheme of brain membrane fractionation used to analyze subcellular localization of TrkB in vivo (see method section for details).DRepresentative Western blotting of TrkB in various brain membrane fractions obtained as described in panel (C). Highlighted lanes represent P3 and P2 fractions, quantified in (E). Detection of PSD95, synaptophysin, and Golgin 97 was used to assess the accuracy of subcellular fractionation.EQuantification of total TrkB distribution between P3 (light membrane fraction) and P2 (synaptosomal fraction) from Western blots exemplified in panel (D) (n = 5 mice/group, 7–12 weeks of age). The TrkB pool is shifted toward the light membrane (P3) fraction in S1/3 KO brains. Data are shown as mean ± SEM and analyzed using two‐way ANOVA with Bonferroni post‐test. ****P < 0.0001.F, GCo‐immunoprecipitation of SORCS1 and SORCS3 with TrkB. TrkB was immunoprecipitated from transiently transfected Chinese hamster ovary cells and the presence of SORCS1 or SORCS3 in the immunoprecipitates documented by Western blotting. Panel input shows levels of the indicated proteins in the cell lysates prior to immunoprecipitation. Panel IP documents co‐immunoprecipitation of SORCS1 (F) and SORCS3 (G) from cells expressing (lanes 3) but not from cells lacking TrkB (lanes 2). The experiment was replicated twice.Source data are available online for this figure. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/29440124), licensed under a CC-BY license. Not internally tested by R&D Systems.
Hu, Mu
Species Glossary
Reactivity: Hu, Mu
WB
Applications: WB
Rat Monoclonal
Host: Rat Monoclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free MAB3067-SP
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AF3067

SorCS3 Antibody

(1 Publication)
100 μg
AF3067
SorCS3 was detected in immersion fixed frozen sections of mouse brain (hippocampus) using 10 µg/mL Goat Anti-Mouse SorCS3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3067) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; Catalog # NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Mu
Species Glossary
Reactivity: Mu
WB, IHC, B/N
Applications: WB, IHC, B/N
Goat Polyclonal
Host: Goat Polyclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Allophycocyanin AF3067A
Biotin AF3067B
CoraFluor 1 AF3067CL1
DyLight 350 AF3067D
DyLight 405 AF3067E
DyLight 488 AF3067K
DyLight 550 AF3067L
DyLight 594 AF3067M
DyLight 650 AF3067W
DyLight 680 AF3067Y
DyLight 755 AF3067Z
FITC AF3067F
HRP AF3067H
Janelia Fluor 525 AF3067JF525
Janelia Fluor 549 AF3067I
Janelia Fluor 646 AF3067J
Janelia Fluor 669 AF3067JF669
PE AF3067P
PerCP AF3067C
mFluor Violet 450 SE AF3067MFV450
mFluor Violet 500 SE AF3067MFV500
mFluor Violet 610 SE AF3067MFV610
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free AF3067-SP
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MAB30671

SorCS3 Antibody (339615) [Unconjugated]

100 μg
Mu
Species Glossary
Reactivity: Mu
WB, IHC
Applications: WB, IHC
Rat Monoclonal
Host: Rat Monoclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Allophycocyanin FAB30671A
Biotin FAB30671B
CoraFluor 1 FAB30671CL1
DyLight 350 FAB30671D
DyLight 405 FAB30671E
DyLight 488 FAB30671K
DyLight 550 FAB30671L
DyLight 594 FAB30671M
DyLight 650 FAB30671W
DyLight 680 FAB30671Y
DyLight 755 FAB30671Z
FITC FAB30671F
HRP FAB30671H
Janelia Fluor 525 FAB30671JF525
Janelia Fluor 549 FAB30671I
Janelia Fluor 646 FAB30671J
Janelia Fluor 669 FAB30671JF669
PE FAB30671P
PerCP FAB30671C
mFluor Violet 450 SE FAB30671MFV450
mFluor Violet 500 SE FAB30671MFV500
mFluor Violet 610 SE FAB30671MFV610
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free MAB30671-SP
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AF3326

SorCS3 Antibody [Unconjugated]

100 μg
Hu
Species Glossary
Reactivity: Hu
WB
Applications: WB
Goat Polyclonal
Host: Goat Polyclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Allophycocyanin AF3326A
Biotin AF3326B
CoraFluor 1 AF3326CL1
DyLight 350 AF3326D
DyLight 405 AF3326E
DyLight 488 AF3326K
DyLight 550 AF3326L
DyLight 594 AF3326M
DyLight 650 AF3326W
DyLight 680 AF3326Y
DyLight 755 AF3326Z
FITC AF3326F
HRP AF3326H
Janelia Fluor 525 AF3326JF525
Janelia Fluor 549 AF3326I
Janelia Fluor 646 AF3326J
Janelia Fluor 669 AF3326JF669
PE AF3326P
PerCP AF3326C
mFluor Violet 450 SE AF3326MFV450
mFluor Violet 500 SE AF3326MFV500
mFluor Violet 610 SE AF3326MFV610
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free AF3326-SP
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3067-SR

Recombinant Mouse SorCS3 Protein, CF

50 μg
Mu
Species Glossary
Reactivity: Mu
Binding Activity
Applications: Binding Activity
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3326-SR

Recombinant Human SorCS3 Protein, CF

50 μg
Hu
Species Glossary
Reactivity: Hu
Binding Activity
Applications: Binding Activity
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NBP1-30615

SorCS3 Antibody - Azide and BSA Free

(2 Publications)
0.5 mg
Hu
Species Glossary
Reactivity: Hu
WB, IHC
Applications: WB, IHC
Rabbit Polyclonal
Host: Rabbit Polyclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Formulations
Formulation Catalog # Availability Price  
Azide and BSA Free NBP1-30615-0.1mg
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H00022986-M01

SorCS3 Antibody (3B12) - Azide and BSA Free

0.1 mg
H00022986-M01
Western Blot: SorCS3 Antibody (3B12) [H00022986-M01] - Detection against Immunogen (34.1 KDa) .
Hu
Species Glossary
Reactivity: Hu
WB, ELISA
Applications: WB, ELISA
Mouse Monoclonal
Host: Mouse Monoclonal
Unconjugated  
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