| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 259-HE-050/CF | |||
| Carrier Free | 259-HE-250/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF-259-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF8239-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB2591-SP | |||
| Carrier Free | MAB2591-500 | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier-Free | NBP2-35069-1mg | |||
| Carrier-Free | NBP2-35069-100ug | |||
| Carrier-Free | NBP2-35069-500ug | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier-Free | NBP2-34920-1mg | |||
| Carrier-Free | NBP2-34920-100ug | |||
| Carrier-Free | NBP2-34920-500ug | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | IC259A | |||
| Carrier Free | IC259G | |||
| Carrier Free | MAB259-SP | |||
| Carrier Free | MAB259-500 | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier-Free | NBP2-35210-1mg | |||
| Carrier-Free | NBP2-35210-100ug | |||
| Carrier-Free | NBP2-35210-500ug | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP2-14082-25ul | |||
![Hb-egf contributes to the angiogenic switch and neovascularization of PNET tumors. (A) Comparison of the average number of hemorrhagic angiogenic islets in wild-type (wt) and Hb-egf mutant (Hb) 9-week-old RT2 mice. (B-C) Comparison of the average (B) tumor burden or (C) tumor number in wild-type and Hb-egf mutant 14-week-old RT2 mice. (D) Western blot analysis of Hb-egf protein expression in total protein extracts from pools of 5 wild-type or 5 Hb-egf mutant tumors. (E-F) Average percentage of (E) dividing tumor cells (phospho-histone H3 positive) or (F) apoptotic cells (TdT-mediated dUTP-biotin nick end-labeling [TUNEL] positive) in wild-type or Hb-egf mutant tumors at 14 weeks of age. (G) Average vessel density (ratio of Meca-32 stained area to total section area) in wild-type or Hb-egf mutant tumors at 14 weeks of age. (H-I) Representative micrographs of (H) wild-type or (I) Hb-egf mutant RT2 tumors stained with Meca-32 (red) and DAPI (blue) (200x); panels are representative of 20 wild-type and 18 Hb-egf RT2 tumors dissected from at least 5 independent mice of each genotype. (N = number of independent mice [A-C] or tumor fields [E-G] analyzed per genotype; 1-2 fields per tumor.) *P < 0.001. **P < 0.01. ***P < 0.05. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/20975924), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/af-259-na_human-hb-egf-affinity-purified-polyclonal-ab-1752025024018.jpg)
![N/A HB-EGF [HRP]](http://images.novusbio.com/fullsize2/HBEGF_DHBEG0_ELISA_1109.jpg "N/A HB-EGF [HRP]")
![N/A HB-EGF [HRP]](http://images.novusbio.com/fullsize2/HBEGF_DHBEG0_ELISA_1108.jpg)
![SDS-Page: Mouse HB-EGF Protein [NBP2-35069]](http://images.novusbio.com/fullsize/Mouse-HB-EGF-Protein-SDS-Page-NBP2-35069-img0001.jpg "SDS-Page: Mouse HB-EGF Protein [NBP2-35069]")
![SDS-Page: Human HB-EGF Protein [NBP2-34920]](http://images.novusbio.com/fullsize/Human-HB-EGF-Protein-SDS-Page-NBP2-34920-img0001.jpg "SDS-Page: Human HB-EGF Protein [NBP2-34920]")
![SDS-Page: Rat HB-EGF Protein [NBP2-35210]](http://images.novusbio.com/fullsize/Rat-HB-EGF-Protein-SDS-Page-NBP2-35210-img0001.jpg "SDS-Page: Rat HB-EGF Protein [NBP2-35210]")
![Immunohistochemistry-Paraffin: HB-EGF Antibody [NBP2-14082] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.](http://images.novusbio.com/fullsize/HB-EGF-Antibody-Immunohistochemistry-Paraffin-NBP2-14082-img0005.jpg "Immunohistochemistry-Paraffin: HB-EGF Antibody [NBP2-14082] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.")
![Immunohistochemistry-Paraffin: HB-EGF Antibody [NBP2-14082] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.](http://images.novusbio.com/fullsize/HB-EGF-Antibody-Immunohistochemistry-Paraffin-NBP2-14082-img0002.jpg)
![Immunohistochemistry-Paraffin: HB-EGF Antibody [NBP2-14082] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.](http://images.novusbio.com/fullsize/HB-EGF-Antibody-Immunohistochemistry-Paraffin-NBP2-14082-img0003.jpg)
![Immunohistochemistry-Paraffin: HB-EGF Antibody [NBP2-14082] - Staining of human liver shows no positivity in hepatocytes as expected.](http://images.novusbio.com/fullsize/HB-EGF-Antibody-Immunohistochemistry-Paraffin-NBP2-14082-img0004.jpg)
![Western Blot: HB-EGF Antibody (JE34-79) [NBP3-32418] - Western blot analysis of HB-EGF on different lysates with Rabbit anti-HB-EGF antibody (NBP3-32418) at 1/1,000 dilution. Lane 1: Jurkat cell lysate Lane 2: K-562 cell lysate Lane 3: 293T cell lysate Lane 4: PC-12 cell lysate Lysates/proteins at 15 ug/Lane. Predicted band size: 23 kDa Observed band size: 23 kDa Exposure time: 1 minute; 4-20% SDS-PAGE gel. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (NBP3-32418) at 1/1,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:100,000 dilution was used for 1 hour at room temperature.](http://images.novusbio.com/fullsize/nbp3-32418_rabbit-hb-egf-mab-je34-79-278202416331232.jpg "Western Blot: HB-EGF Antibody (JE34-79) [NBP3-32418] - Western blot analysis of HB-EGF on different lysates with Rabbit anti-HB-EGF antibody (NBP3-32418) at 1/1,000 dilution. Lane 1: Jurkat cell lysate Lane 2: K-562 cell lysate Lane 3: 293T cell lysate Lane 4: PC-12 cell lysate Lysates/proteins at 15 ug/Lane. Predicted band size: 23 kDa Observed band size: 23 kDa Exposure time: 1 minute; 4-20% SDS-PAGE gel. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (NBP3-32418) at 1/1,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:100,000 dilution was used for 1 hour at room temperature.")
![Immunohistochemistry: HB-EGF Antibody (JE34-79) [NBP3-32418] - Immunohistochemical analysis of paraffin-embedded human heart tissue with Rabbit anti-HB-EGF antibody (NBP3-32418) at 1/200 dilution. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (NBP3-32418) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.](http://images.novusbio.com/fullsize/nbp3-32418_rabbit-hb-egf-mab-je34-79-29820241435221.jpg)
![ELISA: Mouse HB-EGF ELISA Kit (Chemiluminescence) [NBP2-62780] - Samples were spiked with high concentrations of Mouse HB-EGF and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.](http://images.novusbio.com/fullsize/nbp2-62780_mouse-hb-egf-elisa-kit-chemiluminescence-132202416221037.jpg)
![ELISA: Mouse HB-EGF ELISA Kit (Chemiluminescence) [NBP2-62780] - Standard Curve Reference](http://images.novusbio.com/fullsize/nbp2-62780_mouse-hb-egf-elisa-kit-chemiluminescence-432024983560.jpg)