FXYD3 Products

Description

FXYD3, also known as FXYD domain-containing ion transport regulator 3, consists of 3 isoforms, a 87 amino acid isoform that is 9 kDa, a 113 amino acid isoform that is 12 kDa, and a 144 amino acid that is 15 kDa; is membrane located, functions as an inducer of a hyperpolarization-activated chloride current when expressed in Xenopus oocytes, and may be a modulator capable of activating endogenous oocyte channels. Current research is being performed on several diseases and disorders including adenocarcinoma, pancreatic, ductal adenocarcinoma, intrahepatic cholangiocarcinoma, colorectal cancer, cholangiocarcinoma prostate carcinoma, melanoma, pancreatic cancer, pancreatitis, prostate cancer, breast cancer, and prostatitis. The FXYD3 protein has also shown an interaction with SERBP1, FBXL12, NR4A1, MAPK6 and NUDT3, in the regulation of catalytic activity, ion transport, and chloride transport pathways.

Bioinformatics

Entrez	5349 Human
Uniprot	AAH05238 Human NP_001129483 Human NP_001129484 Human NP_005962 Human NP_068710 Human
Product By Gene ID	5349
Alternate Names	Chloride conductance inducer protein Mat-8 FXYD domain containing ion transport regulator 3 FXYD domain-containing ion transport regulator 3 Mammary tumor 8 kDa protein MAT8MAT-8 phospholemman-like protein Phospholemman-like PLMLMGC111076

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