DRAM Products

Description

DRAM is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.

Bioinformatics

Entrez	55332 Human 679937 Rat 71712 Mouse
Uniprot	AAH18435 Human NP_060840 Human Q8N682 Human
Product By Gene ID	55332
Alternate Names	Damage-regulated autophagy modulator DNA damage-regulated autophagy modulator protein 1 DNA-damage regulated autophagy modulator 1 DRAMFLJ11259

Research Areas for DRAM

Find related products by research area and learn more about each of the different research areas below.

Cancer