XBP1 Products

Antibodies
XBP1 Antibody (525904) - (S I ...
XBP1 Antibody (525904) - (S Isoform)
MAB4257
Species: Hu
Applications: ICFlow
Host: Mouse Monoclonal
XBP1 Antibody
XBP1 Antibody
NB100-80861
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
XBP1 Antibody Pair
XBP1 Antibody Pair
H00007494-PW1
Species: Hu
Applications: WB, IP
Lysates
XBP1 Overexpression Lysate (D ...
XBP1 Overexpression Lysate (Denatu...
H00007494-T01
Species: Hu
Applications: WB
XBP1 Overexpression Lysate (N ...
XBP1 Overexpression Lysate (Native)
NBL1-17900
Applications: WB
XBP1 Overexpression Lysate (N ...
XBP1 Overexpression Lysate (Native)
NBP2-09267
Applications: WB
Proteins
XBP1 Recombinant Protein
XBP1 Recombinant Protein
H00007494-P01
Species: Hu
Applications: WB, ELISA, PA
XBP1 Peptide
XBP1 Peptide
NBP1-77253PEP
Species: Hu
Applications: AC
XBP1 Peptide
XBP1 Peptide
NBP1-77252PEP
Species: Hu
Applications: AC
RNAi
XBP1 RNAi
XBP1 RNAi
H00007494-R01
Species: Hu

Description

XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. The protein contains two domains commonly found in transcription factors that confer DNA binding and dimerization capability. This gene product was also separately identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. There is also a recent finding that the same agents that cause an ER stress response, the unfolded protein response, also increase transcription of this gene. This increase in transcription requires an ER stress response consensus binding element in the promoter.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 7494
Alternate Names
  • X-box-binding protein 1
  • XBP-1
  • TREB5
  • XBP2Tax-responsive element-binding protein 5
  • X-box binding protein 1

Research Areas for XBP1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Lipid and Metabolism
Unfolded Protein Response

Bioinformatics Tool for XBP1

Discover related pathways, diseases and genes to XBP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related XBP1 Blog Posts

Check out the latest blog posts on XBP1.
Analysis of Total & pSer724 IRE1 alpha, the Sensor of ER Stress
Inositol-requiring protein 1/IRE1 alpha (also called Endoplasmic Reticulum to Nucleus Signaling 1/ERN1; predicted mol wt 110 kDa) is a serine-threonine protein kinase/endoribonuclease which plays a highly critical role in unfolded protein response/U...    Read more.
IRE1 - an important sensor in the unfolded protein response pathway
During cellular stress the protein folding capacity of the ER is diminished. In order to maintain homeostasis and ensure proper protein folding cells activate the unfolded protein response (UPR), a signaling network consisting of sensors and effect...    Read more.
Read more XBP1 related blogs.