USP4 Products

Antibodies
USP4 Antibody
USP4 Antibody
NBP1-86876
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
USP4 Antibody
USP4 Antibody
NBP2-20834
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
USP4 Antibody
USP4 Antibody
NB110-39054
Species: Hu, Po, Bv, Ca, Mk, Pm, Rb, Equine, Hamster, Rat, Bat
Applications: IHC-P
Host: Rabbit Polyclonal
Lysates
USP4 Overexpression Lysate (N ...
USP4 Overexpression Lysate (Native)
NBL1-17663
Applications: WB
Proteins
USP4 Recombinant Protein
USP4 Recombinant Protein
H00007375-P01
Species: Hu
Applications: WB, ELISA, PA
USP4 Partial Recombinant Prot ...
USP4 Partial Recombinant Protein
H00007375-Q01
Species: Hu
Applications: WB, ELISA, PA
USP4 Recombinant Protein Anti ...
USP4 Recombinant Protein Antigen
NBP1-86876PEP
Species: Hu
Applications: AC
RNAi
USP4 RNAi
USP4 RNAi
H00007375-R02
Species: Hu
USP4 RNAi
USP4 RNAi
H00007375-R01
Species: Hu

Description

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 7375
Alternate Names
  • EC 3.1.2.15
  • MGC149848
  • UNPH
  • Ubiquitous nuclear protein homolog
  • EC 3.4.19.12
  • Ubiquitin-specific-processing protease 4
  • ubiquitin-specific processing protease 4
  • Ubiquitin thiolesterase 4
  • ubiquitin thioesterase 4
  • Deubiquitinating enzyme 4
  • ubiquitin carboxyl-terminal hydrolase 4
  • ubiquitin specific protease 4 (proto-oncogene)
  • ubiquitin carboxyl-terminal esterase 4
  • UNPUnph
  • MGC149849
  • ubiquitin specific peptidase 4 (proto-oncogene)

PTMs for USP4

Learn more about PTMs related to USP4.

Ubiquitination
Cleavage
Phosphorylation

Bioinformatics Tool for USP4

Discover related pathways, diseases and genes to USP4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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