Urocortin Products

Antibodies
Urocortin Antibody (749606)
Urocortin Antibody (749606)
MAB7447
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal

Description

Urocortins 1, 2 and 3 are the mammalian homologs of fish urotensin I. Mammalian urocortin is a member of the corticotropin-releasing hormone(CRH) family that is expressed in a region of the rat midbrain. The distinct expression pattern in discrete brain regions suggests that it influences such behavior as feeding, anxiety and auditory processing. Synthetic human urocortin binds with high affinity to CRH receptors and acts in vitro to release ACTH from dispersed rat anterior pituitary cells. It is suggested that urocortin may be an endogenous CRF-like factor in the brain responsible for the effects of stress on appetite. The gene which encodes urocortin maps to human chromosome 2. Specifically, urocortin III is a specific ligand for CRF type 2 receptor which mediates stress-coping responses. Human urocortin I and III are expressed in the human heart. Urocortin III is also expressed in the pituitary gland, adrenal gland, GI tract, ovary, spleen, brain and kidney.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 7349
Alternate Names
  • urocortin, preproprotein
  • MGC129975
  • MGC129974
  • UROCUI
  • urocortin

PTMs for Urocortin

Learn more about PTMs related to Urocortin.

Phosphorylation
Acetylation
Cleavage
Acylation
Oxidation
Methylation

Bioinformatics Tool for Urocortin

Discover related pathways, diseases and genes to Urocortin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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