UHRF1 Products

Antibodies
UHRF1 Antibody (1A1B1)
UHRF1 Antibody (1A1B1)
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
UHRF1 Antibody
UHRF1 Antibody
NB100-74597
Species: Hu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
UHRF1 Antibody
UHRF1 Antibody
NBP2-20807
Species: Hu
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
UHRF1 Overexpression Lysate
UHRF1 Overexpression Lysate
NBL1-17603
Species: Hu
Applications: WB
Proteins
Recombinant Human UHRF1 Prote ...
Recombinant Human UHRF1 Protein
H00029128-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
UHRF1 Recombinant Protein Ant ...
UHRF1 Recombinant Protein Antigen
NBP2-68720PEP
Species: Hu
Applications: AC

Description

UHRF1 encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 29128
Alternate Names
  • Ubiquitin-like-containing PHD and RING finger domains protein 1
  • EC 6.3.2
  • Ubiquitin-like PHD and RING finger domain-containing protein 1
  • HuNp95
  • Transcription factor ICBP90
  • EC 6.3.2.-
  • Nuclear zinc finger protein Np95
  • ubiquitin-like, containing PHD and RING finger domains, 1
  • Nuclear protein 95
  • huNp95
  • Inverted CCAAT box-binding protein of 90 kDa
  • hNP95
  • Np95
  • E3 ubiquitin-protein ligase UHRF1
  • FLJ21925
  • RNF106MGC138707
  • ICBP90NP95
  • RING finger protein 106
  • ubiquitin-like with PHD and ring finger domains 1

Research Areas for UHRF1

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
Zinc Finger

Bioinformatics Tool for UHRF1

Discover related pathways, diseases and genes to UHRF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related UHRF1 Blog Posts

Check out the latest blog posts on UHRF1.
Chromatin reader domains of DNMT-targeting protein, UHRF1, are responsible for cancerous DNA hypermethylation
By Jamshed Arslan, Pharm. D., PhD. DNA methylation represses transcription of many genes, including tumor suppressor genes. A protein called UHRF1 recruits DNA methyltransferases (DNMTs) to establish and maintain DNA...    Read more.
Read more UHRF1 related blogs.