Hu, Mu, Rt, Bv, Vi, Ca, PmApplications:
WB, ELISA, Flow, ICC/IF, IHC, IHC-PHost:
Species: Hu, Mu, Rt, Bv, Ca, Pm
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Applications: Func, PAGE, Bioactivity
Triosephosphate isomerase (TIM) catalyses the reversible interconversion of G3P and DHAP. Only G3P can be used in glycolysis, therefore TIM is essential for energy production, allowing two molecules of G3P to be produced for every glucose molecule, thereby doubling the energy yield. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
Research Areas for Triosephosphate isomerase
Find related products by research area and learn more about each of the different research areas below.Stem Cell Markers
PTMs for Triosephosphate isomerase
Learn more about PTMs related to Triosephosphate isomerase.Oxidation
Bioinformatics Tool for Triosephosphate isomerase
Discover related pathways, diseases and genes to Triosephosphate isomerase. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related Triosephosphate isomerase Blog Posts
Check out the latest blog posts on Triosephosphate isomerase.
Read more Triosephosphate isomerase related blogs.
|GLO1 Antibodies for Diabetes and Cancer Studies
We at Novus Biologicals are one of the leading antibody suppliers for diabetes research. An aging population, and the increasing incidence of type 2 diabetes, makes it an area of increasing interest - especially as there is often a close link to cance... Read more.