TRIM25 Products

Description

TRIM25 is encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Bioinformatics

Entrez	7706 Human
Uniprot	AAH16924.1 Human NM_005082 Human NP_005073 Human NP_005073.2 Human Q14258 Human
Product By Gene ID	7706
Alternate Names	EC 6.3.2.19 EC 6.3.2.n3 EFPZ147 Estrogen-responsive finger protein RING finger protein 147 RNF147E3 ubiquitin/ISG15 ligase TRIM25 tripartite motif containing 25 tripartite motif-containing 25 Tripartite motif-containing protein 25 Ubiquitin/ISG15-conjugating enzyme TRIM25 zinc finger protein 147 (estrogen-responsive finger protein) Zinc finger protein 147 zinc finger protein-147 ZNF147tripartite motif protein TRIM25

Research Areas for TRIM25

Find related products by research area and learn more about each of the different research areas below.

Cancer
Phospho-Specific
Zinc Finger