TRIM25 Products

Description

TRIM25 is encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Bioinformatics

Entrez	7706 Human
Uniprot	NM_005082 Human NP_005073 Human NP_005073.2 Human AAH16924.1 Human Q14258 Human
Product By Gene ID	7706
Alternate Names	Ubiquitin/ISG15-conjugating enzyme TRIM25 Zinc finger protein 147 Tripartite motif-containing protein 25 EC 6.3.2.n3 Estrogen-responsive finger protein EC 6.3.2.19 zinc finger protein 147 (estrogen-responsive finger protein) zinc finger protein-147 tripartite motif-containing 25 ZNF147tripartite motif protein TRIM25 RNF147E3 ubiquitin/ISG15 ligase TRIM25 EFPZ147 RING finger protein 147 tripartite motif containing 25

Diseases related to TRIM25

Discover more about diseases related to TRIM25.

Malignant Neoplasms
Virus Diseases
Malignant Neoplasm Of Breast
Mammary Neoplasms
Neoplasms
Influenza
Innate Immune Response
Carcinoma
Adenocarcinoma
Carcinogenesis
Rna Virus Infections
Endometrial Polyp
Endometrial Adenocarcinoma
Ovarian Neoplasm
Hepatitis
Malignant Paraganglionic Neoplasm
Hepatitis C
Vesicular Stomatitis
Endometrial Neoplasms
Stomatitis

Pathways for TRIM25

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Cell Proliferation
Immune Response
Cell Growth
Proteolysis
Type I Interferon Production
Translation
Innate Immune Response
Cell Cycle
Conjugation
Localization
Viral Replication
Rig-i Signaling Pathway
Virulence
Methylation
Pathogenesis
Programmed Cell Death
Gene Silencing
Aging
Response To Virus
Tropism

Research Areas for TRIM25

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Cancer
Phospho-Specific
Zinc Finger

PTMs for TRIM25

Learn more about PTMs related to TRIM25.

Ubiquitination
Phosphorylation
Isgylation
Cleavage
Methylation
Dephosphorylation

Bioinformatics Tool for TRIM25

Discover related pathways, diseases and genes to TRIM25. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.