Transglutaminase 3/TGM3 Products

Description

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium dependent. Transglutaminase 3 consists of two polypeptide chains activated from a single precursor protein by proteolysis. Transglutaminase 3 is involved the later stages of cell envelope formation in the epidermis and hair follicle.

Bioinformatics

Entrez	7053 Human
Uniprot	NP_003236 Human NP_003236.3 Human Q08188 Human
Product By Gene ID	7053
Alternate Names	Transglutaminase-3 TGase E transglutaminase-3 TGase-3 protein-glutamine gamma-glutamyltransferase E TG(E) MGC126250 Transglutaminase E TGEMGC126249 EC 2.3.2.13 transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)

Diseases related to Transglutaminase 3/TGM3

Discover more about diseases related to Transglutaminase 3/TGM3.

Carcinoma
Dermatitis
Malignant Neoplasms
Malignant Squamous Cell Neoplasm
Neoplasms
Dermatitis Herpetiformis
Celiac Disease
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm
Cell Invasion
Lymphoma
Esophageal Neoplasms
Mouth Neoplasms
Psoriasis
Squamous Cell Carcinoma Of Esophagus
Dermatologic Disorders
Dermatitis, Atopic
Carcinogenesis
Autoimmune Reaction
Metastatic Malignant Neoplasm To The Lymph Node

Pathways for Transglutaminase 3/TGM3

View related products by pathway and learn more about each of the pathways below.

Keratinocyte Differentiation
Keratinization
Proteolysis
Localization
Cornification
Pathogenesis
Blood Coagulation
Immune Response
Skin Development
Coagulation
Cell Death
Cell Differentiation
Transport
Senescence
Chemotaxis
Cell Growth
Extracellular Matrix Organization
Epithelial Cell Differentiation
Response To Hydrogen Peroxide
Wound Healing

PTMs for Transglutaminase 3/TGM3

Learn more about PTMs related to Transglutaminase 3/TGM3.

Cleavage
Amidation
Methylation
Deamidation

Bioinformatics Tool for Transglutaminase 3/TGM3

Discover related pathways, diseases and genes to Transglutaminase 3/TGM3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.