TORC1 Products

Antibodies
TORC1 Antibody
TORC1 Antibody
NBP1-89865
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TORC1 Antibody
TORC1 Antibody
NBP1-02438
Species: Hu, Mu, Rt, Bv, Fi, Ze
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TORC1 Antibody
TORC1 Antibody
NB100-2352
Species: Hu, Mu, Canine, Equine, Fish, Guinea Pig, Porcine, Rat, Zebrafish, Rhesus Macaque
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
TORC1 Overexpression Lysate ( ...
TORC1 Overexpression Lysate (Native)
NBP2-10919
Applications: WB
TORC1 Overexpression Lysate ( ...
TORC1 Overexpression Lysate (Native)
NBP2-07190
Applications: WB
Proteins
TORC1 Partial Recombinant Pro ...
TORC1 Partial Recombinant Protein
H00023373-Q01
Species: Hu
Applications: WB, ELISA, PA
TORC1 Recombinant Protein Ant ...
TORC1 Recombinant Protein Antigen
NBP1-89865PEP
Species: Hu
Applications: AC
RNAi
TORC1 RNAi
TORC1 RNAi
H00023373-R01
Species: Hu
TORC1 RNAi
TORC1 RNAi
H00023373-R02
Species: Hu

Description

MECT1 (also known as MucoEpidermoid Carcinoma Translocated 1, Transducer of regulated cAMP response element-binding protein 1, TORC1, and Transducer of CREB protein 1) is a nuclear protein that functions as a transcriptional coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1does not appear to modulate CREB1 DNA-binding activity but enhances the interaction of CREB1 with TAF4/TAFII-130. MECT1 translocates with MAML2 (MasterMind-Like Protein 2) to yield a fusion oncogene: t(11;19) (q21;p13). This translocation occurs in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. The novel fusion product that results disrupts the Notch signaling pathway. The fusion protein consists of the N-terminus of MECT1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of MECT1 has been detected in a small number of mucoepidermoid carcinomas. Multiple isoforms have been reported for the MECT1 protein.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 23373
Alternate Names
  • Mucoepidermoid carcinoma translocated protein 1
  • transducer of regulated cAMP response element-binding protein (CREB) 1
  • mucoepidermoid carcinoma translocated 1
  • MECT1CREB-regulated transcription coactivator 1
  • FLJ14027WAMTP1
  • TORC1TORC-1
  • KIAA0616Transducer of regulated cAMP response element-binding protein 1
  • Transducer of CREB protein 1
  • CREB regulated transcription coactivator 1

Research Areas for TORC1

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for TORC1

Learn more about PTMs related to TORC1.

Phosphorylation
Dephosphorylation
Ubiquitination
Deacetylation
Methylation

Bioinformatics Tool for TORC1

Discover related pathways, diseases and genes to TORC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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