Hu, Mu, RtApplications:
WB, ELISA, ICC/IF, IHC, IHC-P, IPHost:
Hu, Mu, Ch, Pm, Xp, ZeApplications:
WB, ICC/IF, IHCHost:
Hu, Mu, Rt, Po, BvApplications:
WB, ICC/IF, IHC, IHC-PHost:
Applications: WB, RNAi SP
TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.
Bioinformatics Tool for TDP-43/TARDBP
Discover related pathways, diseases and genes to TDP-43/TARDBP. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.