Species: Hu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bt, Ca, Eq, Pm, Pm
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
GPR65 (TDAG8), a Lysophospholipid/Lysosphingolipid Receptor, is a molecular target for psychosine, a toxic lipid formed by the breakdown of galactosylceramide (cerebroside). A build-up of psychosine, caused by the lack of galactosylceramidase, results in the death of the myelin-synthesizing cells, oligodendrocytes, which is associated with Krabbe disease. GPR65 has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. ESTs have been isolated from human B-cell/lung/testis, brain/lung/testis, pancreas/spleen, lung/spleen, leukocyte, embryo, kidney, liver/spleen, thyroid, and vessel libraries.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
8477 |
| Alternate Names |
- G protein-coupled receptor 65
- G-protein coupled receptor 65
- psychosine receptor
- T-cell death-associated gene 8 protein
- TDAG8hTDAG8
|
Research Areas for TDAG8/GPR65
Find related products by research area and learn more about each of the different research areas below.
ApoptosisGPCR
![Western Blot TDAG8/GPR65 Antibody (976128) [Unconjugated]](http://images.novusbio.com/fullsize2/TDAG8_MAB10077_Western_Blot_23092.jpg)
![Immunocytochemistry TDAG8/GPR65 Antibody (976128) [Unconjugated]](http://images.novusbio.com/fullsize2/mab10077_human-tdag8-gpr65-mab-clone-976128-immunocytochemistry-32202111118.jpg)
