After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.
HAF018). Specific bands were detected for TDAG8/GPR65 at approximately 85-95 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
NL007) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces. View our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="big_lightbox" target="_blank">
Species: Hu Applications: WB, ICC/IF Host: Mouse Monoclonal
GPR65 (TDAG8), a Lysophospholipid/Lysosphingolipid Receptor, is a molecular target for psychosine, a toxic lipid formed by the breakdown of galactosylceramide (cerebroside). A build-up of psychosine, caused by the lack of galactosylceramidase, results in the death of the myelin-synthesizing cells, oligodendrocytes, which is associated with Krabbe disease. GPR65 has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. ESTs have been isolated from human B-cell/lung/testis, brain/lung/testis, pancreas/spleen, lung/spleen, leukocyte, embryo, kidney, liver/spleen, thyroid, and vessel libraries.
![Western Blot TDAG8/GPR65 Antibody (976128) [Unconjugated]](http://images.novusbio.com/images/antibody/TDAG8_MAB10077_Western_Blot_23092.jpg)
![Immunocytochemistry TDAG8/GPR65 Antibody (976128) [Unconjugated]](http://images.novusbio.com/images/antibody/mab10077_human-tdag8-gpr65-mab-clone-976128-immunocytochemistry-32202111118.jpg)
