TBC1D4 Products

Antibodies
TBC1D4 Antibody (5E6)
TBC1D4 Antibody (5E6)
NBP2-00597
Species: Hu, Mk
Applications: WB, Flow, ICC/IF
Host: Mouse Monoclonal
TBC1D4 Antibody
TBC1D4 Antibody
NB100-57094
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
TBC1D4 Antibody
TBC1D4 Antibody
NBP2-38460
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
TBC1D4 Overexpression Lysate ...
TBC1D4 Overexpression Lysate (Native)
NBP2-07277
Applications: WB
Proteins
TBC1D4 Recombinant Protein An ...
TBC1D4 Recombinant Protein Antigen
NBP2-38880PEP
Species: Hu
Applications: AC
TBC1D4 Recombinant Protein An ...
TBC1D4 Recombinant Protein Antigen
NBP2-38460PEP
Species: Hu
Applications: AC

Description

AS160, also known as TBC1D4, is a 160 kDa Akt substrate that plays a critical role in regulating insulin-stimulated exocytosis of glucose transporter GLUT4. AS-160 contains a Rab GTPase-activating protein domain (GAP), suggesting its potential role in membrane trafficking. Insulin-stimulated phosphorylation of AS160 on threonine 642 is critical for mediating GLUT4 translocation in fat and muscle cells, via inactivation of Rab GAP function. Phosphorylation of Thr642 is also important in mediating TBC1D4 redistribution from low density microsomes to the cytosol in adipocytes.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 9882
Alternate Names
  • TBC1 domain family member 4
  • DKFZp779C0666
  • KIAA0603TBC (Tre-2, BUB2, CDC16) domain-containing protein
  • AS160Acrg embryonic lethality minimal region ortholog
  • Akt substrate of 160 kDa
  • TBC1 domain family, member 4

Research Areas for TBC1D4

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research
Lipid and Metabolism
Phospho-Specific

PTMs for TBC1D4

Learn more about PTMs related to TBC1D4.

Phosphorylation
Biotinylation
Oxidation
Methylation
Cleavage
Dephosphorylation

Bioinformatics Tool for TBC1D4

Discover related pathways, diseases and genes to TBC1D4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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