Sulfatase-2/SULF2 Products

Description

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as Sulfatase 2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]) [supplied by OMIM].

Bioinformatics

Entrez	55959 Human 72043 Mouse
Uniprot	AAH20962 Human NM_198596 Human NP_940998 Human NP_061325 Human NP_061325.1 Human
Product By Gene ID	55959
Alternate Names	EC 3.1.6.14 FLJ90554 EC 3.1.6 FLJ44488 hSulf-2 DKFZp313E091 EC 3.1.6.- SULF-2 extracellular sulfatase Sulf-2 KIAA1247HSULF-2 MGC126411 sulfatase 2

Diseases related to Sulfatase-2/SULF2

Discover more about diseases related to Sulfatase-2/SULF2.

Neoplasms
Malignant Neoplasms
Carcinoma
Liver Carcinoma
Liver Neoplasms
Adenocarcinoma
Carcinogenesis
Lung Neoplasms
Malignant Paraganglionic Neoplasm
Mammary Neoplasms
Malignant Neoplasm Of Lung
Malignant Neoplasm Of Breast
Nervousness
Hepatocarcinogenesis
Adenocarcinoma Of Lung (disorder)
Tumor Progression
Tissue Adhesions
Neoplasm Metastasis
Non-small Cell Lung Carcinoma

Pathways for Sulfatase-2/SULF2

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Sulfation
Cell Growth
Localization
Methylation
Pathogenesis
Secretion
Cell Cycle
Cell Proliferation
Glycosylation
Regeneration
Angiogenesis
Cell Adhesion
Cell Migration
Neural Crest Cell Migration
Aging
Brain Development
Proteolysis
Lung Development
Ossification
Protein Glycosylation

Research Areas for Sulfatase-2/SULF2

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Lipid and Metabolism

PTMs for Sulfatase-2/SULF2

Learn more about PTMs related to Sulfatase-2/SULF2.

Cleavage
Phosphorylation
Methylation
Glycosylation
Sulphation
Acetylation

Bioinformatics Tool for Sulfatase-2/SULF2

Discover related pathways, diseases and genes to Sulfatase-2/SULF2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.