WB, ELISA, ICC/IF, IHC-P, IPHost:
Hu, Mu, Rt, Bv, Ca, PoApplications:
Hu, Mu, RtApplications:
WB, ICC/IF, IHC, IHC-PHost:
Stromal interaction molecule 1 plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores. It acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, it translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit.
Bioinformatics Tool for STIM1
Discover related pathways, diseases and genes to STIM1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.