Sphingosine Kinase 1/SPHK1 Products

Antibodies
Sphingosine Kinase 1/SPHK1 An ...
Sphingosine Kinase 1/SPHK1 Antibod...
H00008877-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Sphingosine Kinase 1/SPHK1 An ...
Sphingosine Kinase 1/SPHK1 Antibod...
AF5536
Species: Hu
Applications: WB, ELISA, IHC, IP, ICC/IF
Host: Sheep Polyclonal
Formulation Catalog # Availability Price  
Antibody Pairs
Sphingosine Kinase 1/SPHK1 An ...
Sphingosine Kinase 1/SPHK1 Antibod...
H00008877-PW2
Species: Hu
Applications: WB, IP
Lysates
Sphingosine Kinase 1/SPHK1 Kn ...
Sphingosine Kinase 1/SPHK1 Knockou...
NBP2-78158
Species: Hu
Sphingosine Kinase 1/SPHK1 Ov ...
Sphingosine Kinase 1/SPHK1 Overexp...
NBP2-06490
Species: Hu
Applications: WB
Proteins
Recombinant Human Sphingosine ...
Recombinant Human Sphingosine Kina...
5536-SK
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Mouse Sphingosine ...
Recombinant Mouse Sphingosine Kina...
6086-SK
Species: Mu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  

Description

Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 8877
Alternate Names
  • SPK
  • EC 2.7.1.91
  • SPK 1
  • SPHKSK 1
  • sphingosine kinase 1

Research Areas for Sphingosine Kinase 1/SPHK1

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for Sphingosine Kinase 1/SPHK1

Learn more about PTMs related to Sphingosine Kinase 1/SPHK1.

Phosphorylation
Cleavage
Dephosphorylation
Methylation
Demethylation
Reduction
Glycosylation
Acetylation
Ubiquitination

Bioinformatics Tool for Sphingosine Kinase 1/SPHK1

Discover related pathways, diseases and genes to Sphingosine Kinase 1/SPHK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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