SPARC Products

Antibodies
SPARC Antibody [Unconjugated] ...
SPARC Antibody [Unconjugated]
AF942
Species: Mu
Applications: WB, IHC, CyTOF-ready, Flow, ICC/IF
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
SPARC Antibody [Unconjugated] ...
SPARC Antibody [Unconjugated]
AF941
Species: Hu
Applications: WB, Simple Western, ELISA, IHC, CyTOF-ready, Flow
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
SPARC Antibody
SPARC Antibody
NBP1-80972
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ELISA Kits
Human SPARC Quantikine ELISA ...
Human SPARC Quantikine ELISA Kit
DSP00
Species: Hu
Applications: ELISA
Human SPARC DuoSet ELISA, 5 P ...
Human SPARC DuoSet ELISA, 5 Plate
DY941-05
Species: Hu
Applications: ELISA
Mouse SPARC ELISA Kit (Colori ...
Mouse SPARC ELISA Kit (Colorimetric)
NBP2-68075
Species: Mu
Applications: ELISA
Lysates
SPARC Overexpression Lysate
SPARC Overexpression Lysate
NBL1-16372
Species: Hu
Applications: WB
Proteins
Recombinant Human SPARC Prote ...
Recombinant Human SPARC Protein, CF
941-SP
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse SPARC Prote ...
Recombinant Mouse SPARC Protein, CF
942-SP
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human SPARC Prote ...
Recombinant Human SPARC Protein
NBP2-35270
Species: Hu
Applications: Func, PAGE, Bioactivity

Description

Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 6678
Alternate Names
  • Osteonectin
  • Secreted protein acidic and rich in cysteine
  • osteonectin
  • Basement-membrane protein 40
  • ONcysteine-rich protein
  • BM-40
  • secreted protein, acidic, cysteine-rich (osteonectin)

Research Areas for SPARC

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication

Bioinformatics Tool for SPARC

Discover related pathways, diseases and genes to SPARC. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related SPARC Blog Posts

Check out the latest blog posts on SPARC.
Caspase 8 - a key mediator of apoptosis
Programmed cell death via apoptosis is a key controlled physiological process instigated by the cell death receptor family, their ligands, and the caspase cysteine protease family. All caspases exist in a precursor form that contains a prodomain, a...    Read more.
GAPDH: More than a housekeeping gene
GAPDH is a 146kD tetramer glycolytic pathway metabolic enzyme composed of four 30-40 kDa subunits. It is responsible for reversibly phosphorylating its substrate glyceraldehyde 3-phosphate within the glycolytic pathway.  Apart from its role in gl...    Read more.
GAPDH (Glyceraldehyde 3-Phosphate Dehydrogenase)
GAPDH is a 146 kD tetramer glycolytic pathway metabolic enzyme responsible for reversibly phosphorylating glyceraldehyde 3-phosphate. It may have other possible functions in transcriptional activation. GAPDH is highly expressed due to this housekeepin...    Read more.
FLICE, FLICE, baby
Cell death via apoptosis is a fundamental cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. All caspases exist in a precursor form compose...    Read more.
Read more SPARC related blogs.