SP1 Products

Antibodies
SP1 Antibody
SP1 Antibody
NB600-232
Species: Hu, Mu, Bovine, Goat, Primate, Porcine, Rat, Chinese Hamster, Rhesus Macaque, Monkey
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SP1 Antibody
SP1 Antibody
Species: Hu, Mu
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SP1 Antibody (1A5)
SP1 Antibody (1A5)
H00006667-M02
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Proteins
SP1 Partial Recombinant Prote ...
SP1 Partial Recombinant Protein
H00006667-Q01
Species: Hu
Applications: WB, ELISA, PA
SP1 Recombinant Protein Antig ...
SP1 Recombinant Protein Antigen
NBP1-89458PEP
Species: Hu
Applications: AC
SP1 Recombinant Protein Antig ...
SP1 Recombinant Protein Antigen
NBP1-85812PEP
Species: Hu
Applications: AC
RNAi
SP1 RNAi
SP1 RNAi
H00006667-R01
Species: Hu

Description

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 6667
Alternate Names
  • TSFP1
  • transcription factor Sp1
  • specificity protein 1
  • Sp1 transcription factor

Research Areas for SP1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Phospho-Specific
Transcription Factors and Regulators

Bioinformatics Tool for SP1

Discover related pathways, diseases and genes to SP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related SP1 Blog Posts

Check out the latest blog posts on SP1.
Nur77 Activation and Tumor Suppression
Nur77 is a member of the steroid/thyroid hormone phosphoprotein receptor superfamily. It is heavily post-translationally modified and rapidly induced in response to androgens and growth factors. It governs fundamental processes such as cell proliferat...    Read more.
Estrogen Related Receptors Play Roles in Cancer and Neurodegeneration
By Eric NeeleyEstrogen receptors come in the form of two distinct forms, ER alpha and ER beta. These nuclear receptors are predominantly activated by the hormone 17-beta-estradiol to control transcription of genes throughout the immune, nervous, car...    Read more.
Read more SP1 related blogs.