SOD2/Mn-SOD Products

Antibodies
SOD2/Mn-SOD Antibody
SOD2/Mn-SOD Antibody
NB100-1992
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Dr, Gp, Gt, Ha, Pm, Rb, Sh, Sq, Xp
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SOD2/Mn-SOD Antibody
SOD2/Mn-SOD Antibody
NBP2-20535
Species: Hu, Mu, Rt, Al, Av
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SOD2/Mn-SOD Antibody (349810) ...
SOD2/Mn-SOD Antibody (349810) [Unc...
MAB3419
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human/Mouse/RatTotal SOD2/Mn- ...
Human/Mouse/RatTotal SOD2/Mn-SOD D...
DYC3419-2
Species: Hu, Mu, Rt
Applications: ELISA
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Human SOD2/Mn-SOD ELISA Kit ( ...
Human SOD2/Mn-SOD ELISA Kit (Color...
KA0528
Species: Hu
Applications: ELISA
Lysates
SOD2/Mn-SOD Overexpression Ly ...
SOD2/Mn-SOD Overexpression Lysate
NBL1-16334
Species: Hu
Applications: WB
SOD2/Mn-SOD Overexpression Ly ...
SOD2/Mn-SOD Overexpression Lysate
NBL1-16333
Species: Hu
Applications: WB
Proteins
Recombinant Human SOD2/Mn-SOD ...
Recombinant Human SOD2/Mn-SOD Protein
NBP1-41138
Species: Hu
Applications: Func, PAGE, Bioactivity
Recombinant Mouse SOD2/Mn-SOD ...
Recombinant Mouse SOD2/Mn-SOD Protein
NBP2-52079
Species: Mu
Applications: PAGE
SOD2/Mn-SOD Recombinant Prote ...
SOD2/Mn-SOD Recombinant Protein An...
NBP1-86169PEP
Species: Hu
Applications: AC

Description

Superoxide dismutase (SOD) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide (1, 2, 3). There are three SOD isoenzymes in mammalian cells. They are: extracellular SOD (EC SOD), copper and zinc-containing SOD (CuZn SOD) and manganese-containing SOD (Mn SOD, SOD-2). The CuZn form contains Cu and Zn ions and exists as a 32 kDa dimer in the cytosol. Mn SOD is an 80 kDa tetramer that contains Mn ion and resides in the mitochondrial matrix. Mn SOD is a tumor necrosis factor (TNF)-inducible enzyme that protects cells from NFmediated apoptosis (4) via superoxide anion detoxification and the subsequent regulation of apoptosis through cytochrome c release and the modulation of the redox state of the mitochondria (6). Mn SOD has also been shown to be a tumor suppressor in human breast cancer (7). Overexpression of this enzyme protects neurons from NMDAand nitric oxide-induced neurotoxicity.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Rat
Product By Gene ID 6648
Alternate Names
  • superoxide dismutase [Mn], mitochondrial
  • IPOB
  • Mn superoxide dismutase
  • MVCD6
  • mangano-superoxide dismutase
  • MNSOD
  • manganese-containing superoxide dismutase
  • EC 1.15.1.1
  • indophenoloxidase B
  • superoxide dismutase 2, mitochondrial

Research Areas for SOD2/Mn-SOD

Find related products by research area and learn more about each of the different research areas below.

Cancer
Diabetes Research
Neuroscience
Tumor Suppressors

Bioinformatics Tool for SOD2/Mn-SOD

Discover related pathways, diseases and genes to SOD2/Mn-SOD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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