SOD2/Mn-SOD Products

Antibodies
SOD2/Mn-SOD Antibody
SOD2/Mn-SOD Antibody
NB100-1992
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Dr, GP, Ha, Mk, Rb, Sh, Sq, Xp
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SOD2/Mn-SOD Antibody
SOD2/Mn-SOD Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SOD2/Mn-SOD Antibody
SOD2/Mn-SOD Antibody
NB100-1969
Species: Hu
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
ELISA Kits
SOD2/Mn-SOD ELISA Kit [HRP]
SOD2/Mn-SOD ELISA Kit [HRP]
KA0528
Species: Hu
Lysates
SOD2/Mn-SOD Overexpression Ly ...
SOD2/Mn-SOD Overexpression Lysate ...
H00006648-T02
Species: Hu
Applications: WB
SOD2/Mn-SOD Overexpression Ly ...
SOD2/Mn-SOD Overexpression Lysate ...
NBL1-16334
Applications: WB
SOD2/Mn-SOD Overexpression Ly ...
SOD2/Mn-SOD Overexpression Lysate ...
NBL1-16333
Applications: WB
Proteins
SOD2/Mn-SOD Recombinant Prote ...
SOD2/Mn-SOD Recombinant Protein
H00006648-P01
Species: Hu
Applications: WB, ELISA, PA
SOD2/Mn-SOD Recombinant Prote ...
SOD2/Mn-SOD Recombinant Protein
NBP1-41138
Species: Hu
Applications: PAGE
SOD2/Mn-SOD Recombinant Prote ...
SOD2/Mn-SOD Recombinant Protein
H00006648-P02
Species: Hu
Applications: WB, ELISA, PA
RNAi
SOD2/Mn-SOD RNAi
SOD2/Mn-SOD RNAi
H00006648-R03
Species: Hu
Applications: RNAi, RNAi SP
SOD2/Mn-SOD RNAi
SOD2/Mn-SOD RNAi
H00006648-R02
Species: Hu
Applications: RNAi, RNAi SP
SOD2/Mn-SOD RNAi
SOD2/Mn-SOD RNAi
H00006648-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Superoxide dismutase (SOD) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide (1, 2, 3). There are three SOD isoenzymes in mammalian cells. They are: extracellular SOD (EC SOD), copper and zinc-containing SOD (CuZn SOD) and manganese-containing SOD (Mn SOD, SOD-2). The CuZn form contains Cu and Zn ions and exists as a 32 kDa dimer in the cytosol. Mn SOD is an 80 kDa tetramer that contains Mn ion and resides in the mitochondrial matrix. Mn SOD is a tumor necrosis factor (TNF)-inducible enzyme that protects cells from NFmediated apoptosis (4) via superoxide anion detoxification and the subsequent regulation of apoptosis through cytochrome c release and the modulation of the redox state of the mitochondria (6). Mn SOD has also been shown to be a tumor suppressor in human breast cancer (7). Overexpression of this enzyme protects neurons from NMDAand nitric oxide-induced neurotoxicity.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Rat
Product By Gene ID 6648
Alternate Names
  • superoxide dismutase [Mn], mitochondrial
  • IPOB
  • Mn superoxide dismutase
  • MVCD6
  • mangano-superoxide dismutase
  • MNSOD
  • manganese-containing superoxide dismutase
  • EC 1.15.1.1
  • indophenoloxidase B
  • superoxide dismutase 2, mitochondrial

Research Areas for SOD2/Mn-SOD

Find related products by research area and learn more about each of the different research areas below.

Cancer
Diabetes Research
Neuroscience
Tumor Suppressors

Bioinformatics Tool for SOD2/Mn-SOD

Discover related pathways, diseases and genes to SOD2/Mn-SOD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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