Smoothelin Products

Antibodies
Smoothelin Antibody (R4A)
Smoothelin Antibody (R4A)
NBP1-97918
Species: Hu, Po, Ca, Ch, Fe, Pm
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
Smoothelin Antibody (885424) ...
Smoothelin Antibody (885424) [Unco...
MAB8278
Species: Hu
Applications: IHC, CyTOF-ready, ICFlow
Host: Mouse Monoclonal
Smoothelin Antibody
Smoothelin Antibody
NBP2-37971
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Smoothelin Overexpression Lys ...
Smoothelin Overexpression Lysate (...
NBL1-16257
Applications: WB
Smoothelin Overexpression Lys ...
Smoothelin Overexpression Lysate (...
NBP2-05688
Applications: WB
Proteins
Recombinant Human Smoothelin ...
Recombinant Human Smoothelin Protein
H00006525-P01
Species: Hu
Applications: WB, ELISA, PA
Smoothelin Recombinant Protei ...
Smoothelin Recombinant Protein Ant...
NBP2-37931PEP
Species: Hu
Applications: AC
Smoothelin Recombinant Protei ...
Smoothelin Recombinant Protein Ant...
NBP2-37971PEP
Species: Hu
Applications: AC

Description

Smoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC like characteristics, such as myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle do not contain smoothelin. Confocal scanning laser microscopy of tissue sections, as well as transfection studies, show a filamentous organization of smoothelin that is different from that of desmin and vimentin. Smoothelin colocalizes with actin stress fibers. Two tissue specific isoforms have been identified: a 59 kDa isoform specific for visceral SMC; and a 100 kDa specific for vascular SMC. Human smoothelin is encoded by a single copy gene which is located on chromosome 22. The distribution of smoothelin positive cells indicates a correlation between smoothelin expression and smooth muscle tissue contractility. Smoothelin is a useful tool in the evaluation of atherosclerotic lesions.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Chicken
Product By Gene ID 6525
Alternate Names
  • SMSMO
  • FLJ38597
  • FLJ35365
  • smoothelin

PTMs for Smoothelin

Learn more about PTMs related to Smoothelin.

Phosphorylation
Cleavage
Acetylation

Bioinformatics Tool for Smoothelin

Discover related pathways, diseases and genes to Smoothelin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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