Species: Hu
Applications: IHC
Host: Goat Polyclonal
Species: Hu, Mu, Bv
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
SHB is an adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. It may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. It may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades, and may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
6461 |
| Alternate Names |
- bA3J10.2
- RP11-3J10.8
- SH2 domain-containing adapter protein B
- SHB (Src homology 2 domain containing) adaptor protein B
- SHB adaptor protein (a Src homology 2 protein)
- Src homology 2 domain containing adaptor protein B
|
Research Areas for SHB
Find related products by research area and learn more about each of the different research areas below.
Phospho-Specific
