RFC4 Products

Description

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Bioinformatics

Entrez	5984 Human
Uniprot	AAH17452 Human NM_002916 Human NP_002907 Human NP_002907.1 Human NP_853551 Human P35249 Human
Product By Gene ID	5984
Alternate Names	A1 37 kDa subunit A1 Activator 1 37 kDa subunit Activator 1 subunit 4 MGC27291 replication factor C (activator 1) 4, 37kDa Replication factor C 37 kDa subunit replication factor C subunit 4 RFC 37 kDa subunit RF-C 37 kDa subunit RFC37replication factor C (activator 1) 4 (37kD)

Research Areas for RFC4

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
DNA Repair