RASAL1 Products

Description

RASAL1 is encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues.

Bioinformatics

Entrez	8437 Human
Uniprot	AAH14420 Human AAH14420.1 Human O95294 Human
Product By Gene ID	8437
Alternate Names	RAS protein activator like 1 (GAP1 like) RASALGAP1 like protein rasGAP-activating-like protein 1

Research Areas for RASAL1

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction