Species: Hu
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Av
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
QPRT encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
23475 |
| Alternate Names |
- EC 2.4.2.19
- nicotinate-nucleotide pyrophosphorylase (carboxylating)
- QAPRTase
- QPRTasenicotinate-nucleotide pyrophosphorylase [carboxylating]
- Quinolinate phosphoribosyltransferase [decarboxylating]
- quinolinate phosphoribosyltransferase
|
