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Purine Nucleoside Phosphorylase/PNP Products

Antibodies
Purine Nucleoside Phosphoryla ...
Purine Nucleoside Phosphorylase/PN...
NBP1-82541
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Lysates
Purine Nucleoside Phosphoryla ...
Purine Nucleoside Phosphorylase/PN...
NBL1-13737
Species: Hu
Applications: WB
Proteins
Recombinant Human PNP Protein ...
Recombinant Human PNP Protein, CF
6486-NP
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Purine Nucleoside Phosphoryla ...
Purine Nucleoside Phosphorylase/PN...
NBP1-82541PEP
Species: Hu
Applications: AC

Description

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq]

Bioinformatics

Product By Gene ID 4860
Alternate Names
  • EC 2.4.2.1
  • FLJ94043
  • FLJ97288
  • Inosine phosphorylase
  • MGC117396
  • MGC125915
  • MGC125916
  • NPFLJ97312
  • nucleoside phosphorylase
  • PNP
  • PRO1837
  • PUNP
  • purine nucleoside phosphorylase
  • purine-nucleoside:orthophosphate ribosyltransferase