PUM1 Products

Description

Pumilio-1 encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Bioinformatics

Product By Gene ID	9698
Alternate Names	HSPUM KIAA0099PUML1 PUM1 PUMH PUMH1 PUMH1pumilio homolog 1 pumilio (Drosophila) homolog 1 pumilio homolog 1 (Drosophila) Pumilio-1 PUML1

Research Areas for PUM1

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Cell Biology