PPP2R3A Products

Description

Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.

Bioinformatics

Entrez	5523 Human
Uniprot	Q06190 Human
Product By Gene ID	5523
Alternate Names	PP2A subunit B isoform R3 isoform PP2A subunit B isoforms B72/B130 PP2A subunit B isoforms B'-PR72/PR130 protein phosphatase 2 (formerly 2A), regulatory subunit B' (PR 72), alphaisoform and (PR 130), beta isoform protein phosphatase 2 (formerly 2A), regulatory subunit B', alpha protein phosphatase 2, regulatory subunit B', alpha serine/threonine-protein phosphatase 2A regulatory subunit B' subunit alpha subunit B, R3 isoform