PPP2R3A Products

Description

PPP2R3A is a gene that codes for a protein with three isoforms, with lengths of 1150, 529, and 414 amino acids and weights of approximately 130, 61, and 48 kDa respectively. PPP2R3A is thought to modulate substrate selectivity and catalytic activity, as well as facilitate in the localization of catalytic enzymes. Current studies are being done on diseases and disorders related to this gene including retinoblastoma, ataxia, immunodeficiency, malaria, neuronitis, and breast cancer. PPP2R3A has also been shown to have interactions with ATXN7L2, PPP2CA, PPP5C, CDC6, and PPP2R1A in pathways such as the signal transduction PKA signaling, CDK5, mTOR, cell cycle regulation, Wnt signaling, glycogen metabolism, and IL-6 signaling pathways.

Bioinformatics

Entrez	5523 Human
Uniprot	NP_002709.2 Human NP_871626 Human Q06190 Human
Product By Gene ID	5523
Alternate Names	PP2A subunit B isoform R3 isoform PP2A subunit B isoforms B72/B130 PP2A subunit B isoforms B'-PR72/PR130 protein phosphatase 2 (formerly 2A), regulatory subunit B' (PR 72), alphaisoform and (PR 130), beta isoform protein phosphatase 2 (formerly 2A), regulatory subunit B', alpha protein phosphatase 2, regulatory subunit B', alpha serine/threonine-protein phosphatase 2A regulatory subunit B' subunit alpha subunit B, R3 isoform