PLC-gamma 2 Products

Antibodies
PLC-gamma 2 Antibody (346404) ...
PLC-gamma 2 Antibody (346404)
MAB3716
Species: Hu, Mu
Applications: WB, ICC
Host: Mouse Monoclonal
PLC-gamma 2 Antibody
PLC-gamma 2 Antibody
NBP1-87558
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PLC-gamma 2 Antibody
PLC-gamma 2 Antibody
H00005336-D01P
Species: Hu
Applications: WB, ELISA, PLA
Host: Rabbit Polyclonal
Antibody Pairs
PLC-gamma 2 Antibody Pair
PLC-gamma 2 Antibody Pair
H00005336-PW1
Species: Hu
Applications: WB, IP
Lysates
PLC-gamma 2 Overexpression Ly ...
PLC-gamma 2 Overexpression Lysate ...
NBL1-14491
Applications: WB
PLC-gamma 2 Overexpression Ly ...
PLC-gamma 2 Overexpression Lysate ...
H00005336-T01
Applications: WB
Proteins
PLC-gamma 2 Recombinant Prote ...
PLC-gamma 2 Recombinant Protein An...
NBP1-87558PEP
Species: Hu
Applications: AC
PLC-gamma 2 Recombinant Prote ...
PLC-gamma 2 Recombinant Protein An...
NBP1-86030PEP
Species: Hu
Applications: AC
RNAi
PLC-gamma 2 RNAi
PLC-gamma 2 RNAi
H00005336-R01
Species: Hu

Description

Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. The phospholipase C gamma-2 (PLCgammaII) is an enzyme that plays a crucial role in intracellular signal transduction pathways. This enzyme is important because of its role in the generation of second messengers following the hydrolysis of phosphatidylinositol 4,5-bisphosphate (1). PLCgammaII has been implicated in collagen-induced signal transduction in platelets and antigen-dependent signaling in B-lymphocytes. It has been suggested that tyrosine kinases activate PLCgammaII (2). It has also been shown that PLCgammaII was required for receptor activator of NF-kappaB ligand-induced (RANKL-induced) osteoclastogenesis by differentially regulating nuclear factor of activated T cells c1 (NFATc1), activator protein-1 (AP1), and NF-kappaB (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 5336
Alternate Names
  • PLCG2
  • phospholipase C, gamma 2 (phosphatidylyinositol-specific)
  • PLC-IV
  • phospholipase C gamma 2
  • Phospholipase C-IV
  • Phospholipase C-gamma-2,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2
  • EC 3.1.4.11
  • Phosphoinositide phospholipase C-gamma-2
  • PLC-gamma-2
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)

Research Areas for PLC-gamma 2

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Phospho-Specific

PTMs for PLC-gamma 2

Learn more about PTMs related to PLC-gamma 2.

Phosphorylation

Bioinformatics Tool for PLC-gamma 2

Discover related pathways, diseases and genes to PLC-gamma 2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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