PLC-gamma 1 Products

Antibodies
PLC-gamma 1 [p Tyr783] Antibo ...
PLC-gamma 1 [p Tyr783] Antibody (1...
MAB74541
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Monoclonal
PLC-gamma 1 Antibody (1016D) ...
PLC-gamma 1 Antibody (1016D) [Unco...
MAB74542
Species: Hu, Mu, Rt
Applications: ICC
Host: Rabbit Monoclonal
Lysates
PLC-gamma 1 Overexpression Ly ...
PLC-gamma 1 Overexpression Lysate ...
NBP2-10838
Applications: WB
Proteins
Recombinant Human PLC-gamma 1 ...
Recombinant Human PLC-gamma 1 Protein
H00005335-Q01
Species: Hu
Applications: WB, ELISA, PA
PLC-gamma 1 Recombinant Prote ...
PLC-gamma 1 Recombinant Protein An...
NBP2-38316PEP
Species: Hu
Applications: AC
PLC-gamma 1 Recombinant Prote ...
PLC-gamma 1 Recombinant Protein An...
NBP2-38317PEP
Species: Hu
Applications: AC
RNAi
PLC-gamma 1 RNAi
PLC-gamma 1 RNAi
H00005335-R02
Species: Hu
Applications: RNAi, RNAi SP
PLC-gamma 1 RNAi
PLC-gamma 1 RNAi
H00005335-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups (1). Phospholipase C gamma 1 (PLC-gamma 1) hydrolyses phosphatidylinositol-4,5-bisphosphate to the second messengers inositol-1,4,5-trisphosphate and diacylglycerol. PLC-gamma 1 also has mitogenic activity upon growth-factor-dependent tyrosine phosphorylation; however, this activity is not dependent on the phospholipase activity of PLC-gamma 1, but requires an SH3 domain (2). Also, results indicate a lipase-independent role of PLC-gamma in the physiological agonist-induced activation of Ca2+ entry (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 5335
Alternate Names
  • triphosphoinositide phosphodiesterase
  • PLC-gamma-1
  • phospholipase C-148
  • PLC-148
  • phosphoinositide phospholipase C
  • Phospholipase C-II
  • phosphoinositidase C
  • Phospholipase C-gamma-1
  • phosphatidylinositol phospholipase C
  • Phosphoinositide phospholipase C-gamma-1
  • monophosphatidylinositol phosphodiesterase
  • gamma 1 (formerly subtype 148)
  • PLC148
  • NCKAP3,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1
  • PLC11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
  • PLC-II1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
  • EC 3.1.4.11
  • phospholipase C, gamma 1

Research Areas for PLC-gamma 1

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Phospho-Specific
Signal Transduction

PTMs for PLC-gamma 1

Learn more about PTMs related to PLC-gamma 1.

Phosphorylation
Glycosylation
Dephosphorylation

Bioinformatics Tool for PLC-gamma 1

Discover related pathways, diseases and genes to PLC-gamma 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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