PKA 2 beta Products

Antibodies
PKA 2 beta Antibody
PKA 2 beta Antibody
NBP1-33773
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PKA 2 beta Antibody
PKA 2 beta Antibody
NBP1-80879
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PKA 2 beta Overexpression Lys ...
PKA 2 beta Overexpression Lysate (...
NBL1-14768
Applications: WB
Proteins
Recombinant Human PKA 2 beta ...
Recombinant Human PKA 2 beta Protein
H00005577-Q01
Species: Hu
Applications: WB, ELISA, PA
PKA 2 beta Recombinant Protei ...
PKA 2 beta Recombinant Protein Ant...
NBP1-80879PEP
Species: Hu
Applications: AC
RNAi
PKA 2 beta RNAi
PKA 2 beta RNAi
H00005577-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5577
Alternate Names
  • RII-BETA
  • cAMP-dependent protein kinase type II-beta regulatory subunit
  • PRKAR2
  • cAMP-dependent protein kinase type II-beta regulatory chain
  • H_RG363E19.2
  • WUGSC:H_RG363E19.2
  • protein kinase, cAMP-dependent, regulatory, type II, beta

Research Areas for PKA 2 beta

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction

PTMs for PKA 2 beta

Learn more about PTMs related to PKA 2 beta.

Phosphorylation
Cleavage
Myristoylation

Bioinformatics Tool for PKA 2 beta

Discover related pathways, diseases and genes to PKA 2 beta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.