PIBF1 Products

Antibodies
PIBF1 Antibody
PIBF1 Antibody
NBP2-19823
Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
PIBF1 Antibody
PIBF1 Antibody
AF5559
Species: Hu
Applications: WB, IHC
Host: Sheep Polyclonal
PIBF1 Antibody (7B7)
PIBF1 Antibody (7B7)
H00010464-M02
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
PIBF1 Overexpression Lysate ( ...
PIBF1 Overexpression Lysate (Native)
NBL1-14389
Applications: WB, ELISA
PIBF1 Overexpression Lysate ( ...
PIBF1 Overexpression Lysate (Denat...
H00010464-T01
Species: Hu
Applications: WB
Proteins
PIBF1 Recombinant Protein
PIBF1 Recombinant Protein
H00010464-P01
Species: Hu
Applications: WB, ELISA, PA
PIBF1 Partial Recombinant Pro ...
PIBF1 Partial Recombinant Protein
H00010464-Q01
Species: Hu
Applications: WB, ELISA, PA
PIBF1 Recombinant Protein Ant ...
PIBF1 Recombinant Protein Antigen
NBP2-49474PEP
Species: Hu
Applications: AC
RNAi
PIBF1 RNAi
PIBF1 RNAi
H00010464-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PIBF (progesterone-induced blocking factor 1) is synthesized during pregnancy in response to progesterone by progesterone receptor-positive T lymphocytes (mostly gamma-delta T cells). In the presence of PIBF, natural killer (NK) cells inhibit the release of perforin from storage granules and, therefore, fail to lyse target cells. In humans, the amount of cells that express PIBF is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. PIBF has a predicted 89 kDa molecular mass; the full-length PIBF is associated with the nucleus, whereas secretion of shorter forms, such a 34 kDa protein is induced by activation of the cell. Research suggests that PIBF functions as a transcription factor in its full-length form, while smaller forms may act as cytokines.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 10464
Alternate Names
  • progesterone-induced-blocking factor 1
  • chromosome 13 open reading frame 24
  • progesterone-induced blocking factor 1
  • PIBF
  • RP11-505F3.1
  • C13orf24
  • KIAA1008
  • progesterone immunomodulatory binding factor 1

PTMs for PIBF1

Learn more about PTMs related to PIBF1.

Phosphorylation
Glycosylation

Bioinformatics Tool for PIBF1

Discover related pathways, diseases and genes to PIBF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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