PI 3-Kinase p85 beta Products

Description

The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 beta). p85 beta is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 beta is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

Bioinformatics

Entrez	18709 Mouse 29741 Rat 5296 Human
Uniprot	NP_005018 Human O00459 Human
Product By Gene ID	5296
Alternate Names	P85B phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) phosphoinositide-3-kinase, regulatory subunit 2 (beta) phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta) phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) PI3K regulatory subunit beta PI3-kinase regulatory subunit beta PI3-kinase subunit p85-beta ptdIns-3-kinase regulatory subunit beta ptdIns-3-kinase regulatory subunit p85-beta

Research Areas for PI 3-Kinase p85 beta

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Phospho-Specific
Signal Transduction